Lipids shape brain function through ion channel and receptor modulations: Physiological mechanisms and clinical perspectives

S Incontro, ML Musella, M Sammari… - Physiological …, 2025 - journals.physiology.org
Lipids represent the most abundant molecular type in the brain, with a fat content of∼ 60%
of the dry brain weight in humans. Despite this fact, little attention has been paid to …

Carbachol models of REM sleep: recent developments and new directions.

L Kubin - Archives italiennes de biologie, 2001 - architalbiol.org
Since the early'60s, injections of a broad-spectrum muscarinic cholinergic agonist,
carbachol, into the medial pontine reticular formation (mPRF) of cats have been extensively …

Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation

KB Nelson, JK Grether, LA Croen… - Annals of …, 2001 - Wiley Online Library
There has been little exploration of major biologic regulators of cerebral development in
autism. In archived neonatal blood of children with autistic spectrum disorders (n= 69) …

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons

P Bourgin, S Huitron-Resendiz, AD Spier… - Journal of …, 2000 - Soc Neuroscience
The hypocretins (hcrts), also known as orexins, are two recently identified excitatory
neuropeptides that in rat are produced by∼ 1200 neurons whose cell bodies are located in …

Direct and indirect excitation of laterodorsal tegmental neurons by hypocretin/orexin peptides: implications for wakefulness and narcolepsy

S Burlet, CJ Tyler, CS Leonard - Journal of Neuroscience, 2002 - Soc Neuroscience
Compelling evidence links the recently discovered hypothalamic peptides Hypocretin/Orexin
(Hcrt/Orx) to rapid eye movement sleep (REM) control and the sleep disorder narcolepsy, yet …

Effects of Vasoactive Intestinal Polypeptide on Neurones of the Rat Suprachiasmatic Nuclei In Vitro

HE Reed, DJ Cutler, TM Brown, J Brown… - Journal of …, 2002 - Wiley Online Library
The suprachiasmatic nuclei (SCN) of the hypothalamus house the main circadian
pacemaker in mammals. Vasoactive intestinal polypeptide (VIP) is the most abundant …

Vasoactive intestinal polypeptide phase-advances the rat suprachiasmatic nuclei circadian pacemaker in vitro via protein kinase A and mitogen-activated protein …

A Meyer-Spasche, HD Piggins - Neuroscience letters, 2004 - Elsevier
The firing activity of suprachiasmatic nuclei (SCN) neurones in vitro shows a circadian
rhythm with the peak in average firing frequency during the middle of the projected day …

[PDF][PDF] Cambios fisiológicos en el sueño

R Navarrete - Revista Ecuatoriana de Neurología, 2013 - revecuatneurol.com
Durante el sueño no solo ocurren los cambios más conocidos como las alteraciones del
electroencefalograma (EEG), movimientos oculares rápidos (MOR) o alteraciones del tono …

Sleep-inducing factors

F García-García, E Acosta-Peña… - CNS & Neurological …, 2009 - ingentaconnect.com
Kuniomi Ishimori and Henri Piéron were the first researchers to introduce the concept and
experimental evidence for a chemical factor that would presumably accumulate in the brain …

VPAC receptor modulation of neuroexcitability in intracardiac neurons: dependence on intracellular calcium mobilization and synergistic enhancement by PAC1 …

WI DeHaven, J Cuevas - Journal of Biological Chemistry, 2004 - ASBMB
Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal
polypeptide (VIP) have been found within mammalian intracardiac ganglia, but the cellular …