[HTML][HTML] The gut-brain connection: Exploring the influence of the gut microbiota on neuroplasticity and neurodevelopmental disorders

F Damiani, S Cornuti, P Tognini - Neuropharmacology, 2023 - Elsevier
Neuroplasticity refers to the ability of brain circuits to reorganize and change the properties
of the network, resulting in alterations in brain function and behavior. It is traditionally …

[HTML][HTML] Microglia in epilepsy

C Yu, X Deng, D Xu - Neurobiology of Disease, 2023 - Elsevier
Epilepsy is one of most common chronic neurological disorders, and the antiseizure
medications developed by targeting neurocentric mechanisms have not effectively reduced …

Luteolin treatment ameliorates brain development and behavioral performance in a mouse model of CDKL5 deficiency disorder

M Tassinari, N Mottolese, G Galvani, D Ferrara… - International Journal of …, 2022 - mdpi.com
CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disease caused
by mutations in the X-linked CDKL 5 gene, is characterized by early-onset epilepsy …

CDKL5 deficiency disorder-related epilepsy: a review of current and emerging treatment

W Hong, I Haviland, E Pestana-Knight, JL Weisenberg… - CNS drugs, 2022 - Springer
Abstract Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a
developmental and epileptic encephalopathy with infantile-onset epilepsy. Most individuals …

Intermittent hypoxic conditioning restores neurological dysfunction of mice induced by long‐term hypoxia

G Li, Y Guan, Y Gu, M Guo, W Ma… - CNS Neuroscience …, 2023 - Wiley Online Library
Background Central nervous system diseases are associated with hypoxia, which usually
cause irreversible nerve damage, but the underlying mechanism is unclear and effective …

Voluntary running improves behavioral and structural abnormalities in a mouse model of CDKL5 deficiency disorder

N Mottolese, B Uguagliati, M Tassinari, CB Cerchier… - Biomolecules, 2023 - mdpi.com
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare
neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is …

Touchscreen cognitive deficits, hyperexcitability and hyperactivity in males and females using two models of Cdkl5 deficiency

A Adhikari, FKB Buchanan, TA Fenton… - Human molecular …, 2022 - academic.oup.com
Many neurodevelopmental disorders (NDDs) are the result of mutations on the X
chromosome. One severe NDD resulting from mutations on the X chromosome is CDKL5 …

[HTML][HTML] A systematic review and multilevel meta-analysis of the prenatal and early life stress effects on rodent microglia, astrocyte, and oligodendrocyte density and …

R Orso, KC Creutzberg, FS Lumertz… - Neuroscience & …, 2023 - Elsevier
Exposure to stress during early development may lead to altered neurobiological functions,
thus increasing the risk for psychiatric illnesses later in life. One potential mechanism …

GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice

S Sonny, H Yuan, S Chen, MR Duncan, P Chen… - Scientific reports, 2023 - nature.com
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are among the
most common morbidities affecting extremely premature infants who receive oxygen …

[HTML][HTML] Role of Plant Phytochemicals: Resveratrol, Curcumin, Luteolin and Quercetin in Demyelination, Neurodegeneration, and Epilepsy

M Grabarczyk, W Justyńska, J Czpakowska… - Antioxidants, 2024 - mdpi.com
Polyphenols are an important group of biologically active compounds present in almost all
food sources of plant origin and are primarily known for their anti-inflammatory and …