C Yu, X Deng, D Xu - Neurobiology of Disease, 2023 - Elsevier
Epilepsy is one of most common chronic neurological disorders, and the antiseizure medications developed by targeting neurocentric mechanisms have not effectively reduced …
M Tassinari, N Mottolese, G Galvani, D Ferrara… - International Journal of …, 2022 - mdpi.com
CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disease caused by mutations in the X-linked CDKL 5 gene, is characterized by early-onset epilepsy …
W Hong, I Haviland, E Pestana-Knight, JL Weisenberg… - CNS drugs, 2022 - Springer
Abstract Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a developmental and epileptic encephalopathy with infantile-onset epilepsy. Most individuals …
G Li, Y Guan, Y Gu, M Guo, W Ma… - CNS Neuroscience …, 2023 - Wiley Online Library
Background Central nervous system diseases are associated with hypoxia, which usually cause irreversible nerve damage, but the underlying mechanism is unclear and effective …
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is …
A Adhikari, FKB Buchanan, TA Fenton… - Human molecular …, 2022 - academic.oup.com
Many neurodevelopmental disorders (NDDs) are the result of mutations on the X chromosome. One severe NDD resulting from mutations on the X chromosome is CDKL5 …
Exposure to stress during early development may lead to altered neurobiological functions, thus increasing the risk for psychiatric illnesses later in life. One potential mechanism …
S Sonny, H Yuan, S Chen, MR Duncan, P Chen… - Scientific reports, 2023 - nature.com
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are among the most common morbidities affecting extremely premature infants who receive oxygen …
M Grabarczyk, W Justyńska, J Czpakowska… - Antioxidants, 2024 - mdpi.com
Polyphenols are an important group of biologically active compounds present in almost all food sources of plant origin and are primarily known for their anti-inflammatory and …