Prions are misfolded infectious proteins responsible for a group of fatal neurodegenerative
diseases termed transmissible spongiform encephalopathy or prion diseases. Chronic …

The spread of chronic wasting disease (CWD) during the last six decades has resulted in
cervid populations of North America where CWD has become enzootic. This insidious …

Background An unmet clinical need in Parkinson's disease (PD) is to identify biomarkers for
diagnosis, preferably in peripherally accessible tissues such as skin. Immunohistochemical …

Background Identification of a peripheral biomarker is a major roadblock in the diagnosis of
PD. Immunohistological identification of p‐serine 129 α‐synuclein in the submandibular …

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that
affects members of the cervidae family. The infectious agent is a misfolded isoform (PrPSC) …

Adult-onset neurodegenerative disorders, like Parkinson's disease (PD) and dementia with
Lewy bodies (DLB), that share the accumulation of aggregated α-synuclein (αSyn agg) as …

Chronic wasting disease (CWD) is a prion disease found in both free-ranging and farmed
cervids. Susceptibility of these animals to CWD is governed by various exogenous and …

To date, chronic wasting disease (CWD) is the most infectious form of prion disease affecting
several captive, free ranging and wild cervid species. Responsible for marked population …

Prion diseases are transmissible neurodegenerative disorders that affect humans and
ruminant species consumed by humans. Ruminant prion diseases include bovine …

Chronic wasting disease (CWD) is a relatively new and burgeoning prion epidemic of deer,
elk, reindeer, and moose, which are members of the cervid family. While the disease was …