In recent decades, due to insufficient concentration at the lesion site, low bioavailability and
increasingly serious resistance, antibiotics have become less and less dominant in the …

Abstract Intracellular Methicillin-Resistant Staphylococcus aureus (MRSA) remains a major
factor of refractory and recurrent infections, which cannot be well addressed by antibiotic …

Inhibition of overexpressed enzymes is among the most promising approaches for targeted
cancer treatment. However, many cancer-expressed enzymes are “nonlethal,” in that the …

Infections induced by intracellular pathogens are difficult to eradicate due to poor
penetration of antimicrobials into cell membranes. It is of great importance to develop a new …

Infections by intracellular pathogens are difficult to treat because of the poor accessibility of
antibiotics to the pathogens encased by host cell membranes. As such, a strategy that can …

Following a myocardial infarction (MI) or stroke, the excessive generation of reactive oxygen
species (ROS) within a brief timeframe may induce a pronounced inflammatory reaction …

Intracellular bacteria are the major cause of serious infections including sepsis and
peritonitis, but face great challenges in fighting against the stubborn intracellular small …

Biomaterial-associated infection (BAI) is a kind of serious post-operative complication in
orthopaedic surgery. Antibiotic-loaded bone cement shines a light on BAI prevention for …

Multifunctional bioimaging probes based on metal clusters have multiple characteristics of
metal clusters and functional conjugates, and their development has broad application …

Adipocytes play a critical role in energy storage and endocrine signaling and are associated
with various diseases such as cancer and diabetes. Facile strategies to engineer adipocytes …