Recent advances of intraocular lens materials and surface modification in cataract surgery

C Luo, H Wang, X Chen, J Xu, H Yin… - … in Bioengineering and …, 2022 - frontiersin.org
Advances in cataract surgery have increased the demand for intraocular lens (IOL)
materials. At present, the progress of IOL materials mainly contains further improving …

Therapeutic ophthalmic lenses: a review

N Toffoletto, B Saramago, AP Serro - Pharmaceutics, 2020 - mdpi.com
An increasing incidence of eye diseases has been registered in the last decades in
developed countries due to the ageing of population, changes in lifestyle, environmental …

Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification

X Zhang, K Lai, S Li, J Wang, J Li, W Wang, S Ni, B Lu… - Bioactive Materials, 2022 - Elsevier
Cataract is the leading cause of visual impairment, and posterior capsular opacification
(PCO) is the most common long-term complication of modern cataract surgery, which can …

Centrifugally concentric ring-patterned drug-loaded polymeric coating as an intraocular lens surface modification for efficient prevention of posterior capsular …

D Lu, Y Han, D Liu, S Chen, J Qie, J Qu, Q Lin - Acta Biomaterialia, 2022 - Elsevier
Posterior capsular opacification (PCO) is the main postoperative complication after
intraocular lens (IOL) implantation in cataract surgery, because of the proliferation of the …

Dual drug delivery from hydrophobic and hydrophilic intraocular lenses: in-vitro and in-vivo studies

A Topete, J Tang, X Ding, HP Filipe, JA Saraiva… - Journal of Controlled …, 2020 - Elsevier
Posterior capsule opacification (PCO) still remains the most frequent long term complication
after cataract surgery, while endophthalmitis is rare but severe and should be prevented at …

Factors affecting posterior capsule opacification in the development of intraocular lens materials

G Cooksley, J Lacey, MK Dymond, S Sandeman - Pharmaceutics, 2021 - mdpi.com
Posterior capsule opacification (PCO) is the most common complication arising from the
corrective surgery used to treat cataract patients. PCO arises when lens epithelial cells …

Anti-angiogenic activity of bevacizumab-bearing dexamethasone-loaded PLGA nanoparticles for potential intravitreal applications

J Liu, X Zhang, G Li, F Xu, S Li, L Teng… - International Journal of …, 2019 - Taylor & Francis
Purpose Age-related macular degeneration is a multifactorial disease involving
inflammation and choroidal neovascularization. Vascular endothelial growth factor (VEGF) …

Supercritical fluid technology for the development of innovative ophthalmic medical devices: Drug loaded intraocular lenses to mitigate posterior capsule opacification

K Ongkasin, Y Masmoudi, CM Wertheimer… - European Journal of …, 2020 - Elsevier
Supercritical impregnation technology was applied to load acrylic intraocular lenses (IOLs)
with methotrexate to produce a sustained drug delivery device to mitigate posterior capsule …

Intraocular lenses as drug delivery devices

A Topete, B Saramago, AP Serro - International journal of pharmaceutics, 2021 - Elsevier
Cataract surgery is one of the most common and safe surgical procedures nowadays.
However, it is not free of risks as endophthalmitis, ocular inflammation and posterior capsule …

Spin-coating-based facile annular photodynamic intraocular lens fabrication for efficient and safer posterior capsular opacification prevention

D Lu, H Wang, C Feng, T Bai, B Xu, Y Wei… - … Applied Materials & …, 2022 - ACS Publications
Posterior capsular opacification (PCO) is the most common complication after cataract
surgery, which is primarily caused by the proliferation of the residual lens epithelial cells …