While memories are often thought of as flashbacks to a previous experience, they do not simply conserve veridical representations of the past but must continually integrate new …
Animals associate cues with outcomes and update these associations as new information is presented. This requires the hippocampus, yet how hippocampal neurons track changes in …
Reliable sensory discrimination must arise from high-fidelity neural representations and communication between brain areas. However, how neocortical sensory processing …
JC Jimenez, JE Berry, SC Lim, SK Ong… - Nature …, 2020 - nature.com
Abstract Ventral hippocampal CA1 (vCA1) projections to the amygdala are necessary for contextual fear memory. Here we used in vivo Ca2+ imaging in mice to assess the temporal …
The hippocampus and its extended network contribute to encoding and recall of episodic experiences. Drawing from recent anatomical, physiological, and behavioral studies, we …
A de Groot, BJG van den Boom, RM van Genderen… - Elife, 2020 - elifesciences.org
Miniaturized fluorescence microscopes (miniscopes) have been instrumental to monitor neural signals during unrestrained behavior and their open-source versions have made …
An" elegant"," engrossing"(Carol Tavris, Wall Street Journal) examination of what we think we know about the brain and why--despite technological advances--the workings of our …
C Guo, GJ Blair, M Sehgal, FN Sangiuliano Jimka… - Science …, 2023 - science.org
Imaging large-population, single-cell fluorescent dynamics in freely behaving animals larger than mice remains a key endeavor of neuroscience. We present a large-field-of-view open …
Recent experiments have revealed that neural population codes in many brain areas continuously change even when animals have fully learned and stably perform their tasks …