Obesity in type 1 diabetes: pathophysiology, clinical impact, and mechanisms

KD Corbin, KA Driscoll, RE Pratley, SR Smith… - Endocrine …, 2018 - academic.oup.com
There has been an alarming increase in the prevalence of obesity in people with type 1
diabetes in recent years. Although obesity has long been recognized as a major risk factor …

[HTML][HTML] Hepatic steatosis in type 1 diabetes

SE Regnell, A Lernmark - The review of diabetic studies: RDS, 2011 - ncbi.nlm.nih.gov
Islet autoimmunity in type 1 diabetes results in the loss of the pancreatic β-cells. The
consequences of insulin deficiency in the portal vein for liver fat are poorly understood …

Fatty liver index and hepatic steatosis index for prediction of non‐alcoholic fatty liver disease in type 1 diabetes

L Sviklāne, E Olmane, Z Dzērve… - Journal of …, 2018 - Wiley Online Library
Abstract Background and Aim Little is known about the diagnostic value of hepatic steatosis
index (HSI) and fatty liver index (FLI), as well as their link to metabolic syndrome in type 1 …

Diabetes-induced hepatic pathogenic damage, inflammation, oxidative stress, and insulin resistance was exacerbated in zinc deficient mouse model

C Zhang, X Lu, Y Tan, B Li, X Miao, L Jin, X Shi… - PloS one, 2012 - journals.plos.org
Objectives Zinc (Zn) deficiency often occurs in the patients with diabetes. Effects of Zn
deficiency on diabetes-induced hepatic injury were investigated. Methods Type 1 diabetes …

[HTML][HTML] Pathophysiology of diabetic hepatopathy and molecular mechanisms underlying the hepatoprotective effects of phytochemicals

L Mobasheri, M Ahadi, AB Namdar, MS Alavi… - Biomedicine & …, 2023 - Elsevier
Patients with diabetes are at risk for liver disorders including glycogen hepatopathy, non-
alcoholic fatty liver disease, cirrhosis, and hepatic fibrosis. The pathophysiological …

[HTML][HTML] Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease

N Baršić, I Lerotić, L Smirčić-Duvnjak… - World Journal of …, 2012 - ncbi.nlm.nih.gov
High prevalence of non-alcoholic fatty liver disease (NAFLD) and very diverse outcomes that
are related to disease form and severity at presentation have made the search for …

Effect and the probable mechanisms of silibinin in regulating insulin resistance in the liver of rats with non-alcoholic fatty liver

J Yao, M Zhi, X Gao, P Hu, C Li, X Yang - Brazilian Journal of Medical …, 2013 - SciELO Brasil
Our previous study has shown that reduced insulin resistance (IR) was one of the possible
mechanisms for the therapeutic effect of silibinin on non-alcoholic fatty liver disease …

[HTML][HTML] Translational approaches: from fatty liver to non-alcoholic steatohepatitis

N Rosso, NC Chavez-Tapia, C Tiribelli… - World journal of …, 2014 - ncbi.nlm.nih.gov
Over the past few decades, non-alcoholic fatty liver disease (NAFLD) has become one, if not
the most common, cause of chronic liver disease affecting both adults and children. The …

[HTML][HTML] Prevalence of non-alcoholic fatty liver disease (NAFLD) and its association with surrogate markers of insulin resistance in patients with type 1 diabetes

M de Vries, J Westerink, F El-Morabit… - Diabetes Research and …, 2022 - Elsevier
Aims Assess prevalence of hepatic steatosis (HS) and of fibrosis in an unselected
population of patients with type 1 diabetes. Describe their clinical profile and explore the …

[HTML][HTML] Potential impact of Paracentrotus lividus extract on diabetic rat models induced by high fat diet/streptozotocin

AM Soliman - The Journal of Basic & Applied Zoology, 2016 - Elsevier
Antioxidant therapy has been thought to be effectual for the prevention and treatment of
various diseases including diabetes. Therefore, the present study was designed to …