The Krüppel-like factor (KLF) family of transcription factors regulates diverse biological
processes that include proliferation, differentiation, growth, development, survival, and …

Krüppel-like factors (KLFs) are a family of DNA-binding transcriptional regulators with
diverse and essential functions in a multitude of cellular processes, including proliferation …

Abstract KLF5 (Kruppel-like factor 5) is a basic transcription factor binding to GC boxes at a
number of gene promoters and regulating their transcription. KLF5 is expressed during …

Advanced prostate cancer (PCa) often develops bone metastasis, for which therapies are
very limited and the underlying mechanisms are poorly understood. We report that bone …

Transforming growth factor beta (TGF-β) is a multi-functional polypeptide that plays a critical
role in regulating a broad range of cellular functions and physiological processes. Signaling …

It has become increasingly clear that microRNAs (miRNAs) play important roles in
tumorigenesis and metastasis. Recently, miR-203 was reported as a suppressor microRNA …

The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to
continue to proliferate, cancer cells must somehow uncouple themselves from the many …

LncRNA DANCR suppresses differentiation of epithelial cells, however, its function in
prostate cancer development is still unknown. In the present study, we found the expression …

Inactivation of phosphatase and tensin homolog (PTEN) is prevalent in human prostate
cancer and causes high-grade adenocarcinoma with a long latency. Cancer-associated …

CXCL5 is overexpressed in colorectal cancer (CRC) and promotes distant metastasis and
angiogenesis of tumors; however, the underlying mechanism that mediates CXCL5 …