Genetic admixture in Brazil

SDJ Pena, FR Santos… - American Journal of …, 2020 - Wiley Online Library
We review studies from our laboratories using different molecular tools to characterize the
Amerindian, European and African ancestry of Brazilians. Initially we used uniparental DNA …

[PDF][PDF] Evolutionary genetics and admixture in African populations

A Pfennig, LN Petersen, P Kachambwa… - Genome Biology and …, 2023 - academic.oup.com
As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

[HTML][HTML] Genetic consequences of the transatlantic slave trade in the Americas

SJ Micheletti, K Bryc, SGA Esselmann… - The American Journal of …, 2020 - cell.com
According to historical records of transatlantic slavery, traders forcibly deported an estimated
12.5 million people from ports along the Atlantic coastline of Africa between the 16th and …

Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil

MS Naslavsky, MO Scliar, GL Yamamoto… - Nature …, 2022 - nature.com
As whole-genome sequencing (WGS) becomes the gold standard tool for studying
population genomics and medical applications, data on diverse non-European and admixed …

The genetic legacy of African Americans from Catoctin furnace

É Harney, S Micheletti, KS Bruwelheide, WA Freyman… - Science, 2023 - science.org
Few African Americans have been able to trace family lineages back to ancestors who died
before the 1870 United States Census, the first in which all Black people were listed by …

The genomic impact of European colonization of the Americas

L Ongaro, MO Scliar, R Flores, A Raveane, D Marnetto… - Current Biology, 2019 - cell.com
The human genetic diversity of the Americas has been affected by several events of gene
flow that have continued since the colonial era and the Atlantic slave trade. Moreover …

Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies

MH Gouveia, AR Bentley, TP Leal… - Nature …, 2023 - nature.com
European-ancestry populations are recognized as stratified but not as admixed, implying
that residual confounding by locus-specific ancestry can affect studies of association …

ACE2 polymorphisms as potential players in COVID-19 outcome

AS Khayat, PP de Assumpção, BC Meireles Khayat… - PLoS …, 2020 - journals.plos.org
The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the
WHO in March 2020. Currently, there are more than 5 million cases worldwide, and the …

Community-engaged ancient DNA project reveals diverse origins of 18th-century African descendants in Charleston, South Carolina

RE Fleskes, GS Cabana, JK Gilmore… - Proceedings of the …, 2023 - National Acad Sciences
In this study, we present the results of community-engaged ancient DNA research initiated
after the remains of 36 African-descended individuals dating to the late 18th century were …

Understanding and controlling asthma in Latin America: A review of recent research informed by the SCAALA programme

PJ Cooper, CA Figueiredo, A Rodriguez… - Clinical and …, 2023 - Wiley Online Library
Asthma is an important health concern in Latin America (LA) where it is associated with
variable prevalence and disease burden between countries. High prevalence and morbidity …