The precise orchestration of hormonal regulation at all levels of the hypothalamic-pituitary-
gonadal axis is essential for normal reproductive function and fertility. The pulsatile secretion …

Reproduction and fertility are regulated via hormones of the hypothalamic‐pituitary‐gonadal
(HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and …

The 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) isoenzymes are
responsible for the oxidation and isomerization of Δ5-3β-hydroxysteroid precursors into Δ4 …

Neurohormones similar to those of mammals are carried in fish by hypothalamic nerve fibers
to regulate directly follicle-stimulating hormone (FSH) and luteinizing hormone (LH) …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

Mammalian reproductive cycles are controlled by an intricate interplay between the
hypothalamus, pituitary and gonads. Central to the function of this axis is the ability of the …

The orphan nuclear receptor steroidogenic factor 1 (SF-1, also called Ad4BP and officially
designated NR5A1) has emerged as an essential regulator of endocrine development and …

The pituitary gonadotropin hormones, FSH and LH, are essential for fertility. Containing an
identical α-subunit (CGA), they are comprised of unique β-subunits, FSHβ and LHβ …

Since its discovery in the early 1990s, the orphan nuclear receptor SF-1 has been attributed
a central role in the development and differentiation of steroidogenic tissues. SF-1 controls …

The hypothalamic–pituitary–gonadal axis (HPG) plays vital roles in reproduction and steroid
hormone production in both sexes. The focus of this review is upon gene structures, receptor …