Dexmedetomidine is an α 2-adrenoceptor agonist with sedative, anxiolytic, sympatholytic,
and analgesic-sparing effects, and minimal depression of respiratory function. It is potent …

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Background Dexmedetomidine produces sedation while maintaining a degree of
arousability and may reduce the duration of mechanical ventilation and delirium among …

Objectives: Single-injection erector spinae plane block (ESPB) provides good control of pain
relief after open thoracotomy surgeries. However, the duration of pain relief does not last …

Methods: A narrative review after extensive PubMed search was performed from 1950 to
present on October 21st 2021. The language of the publications was restricted to English …

Abstract Background The Bispectral Index (BIS) and the Patient State Index (PSI) are
commonly used measures to assess intraoperative sedation depth. However, model …

Pharmacological considerations in the elderly : Current Opinion in Anesthesiology
Pharmacological considerations in the elderly : Current Opinion in Anesthesiology Log in or …

Management of acute perioperative pain in the geriatric patient can be challenging as the
physiologic and pharmacokinetic changes associated with aging may predispose older …

Background: Desaturation during painless gastroscopy in aged patients leads to
discontinuation of the procedure, prolonged manipulation time and increased risk of severe …

For decades, the comfort and safety of patients who are undergoing mechanical ventilation
in the intensive care unit (ICU) entailed deep sedation, the nearly ubiquitous administration …