The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies

S Elad, N Yarom, Y Zadik… - CA: a cancer journal …, 2022 - Wiley Online Library
Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that
affects patients' function, quality of life, and ability to tolerate treatment. In certain patients …

Immune-related adverse events of immune checkpoint inhibitors: a review

Q Yin, L Wu, L Han, X Zheng, R Tong, L Li… - Frontiers in …, 2023 - frontiersin.org
Since the first Immune Checkpoint Inhibitor was developed, tumor immunotherapy has
entered a new era, and the response rate and survival rate of many cancers have also been …

Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy: ASCO guideline update

BJ Schneider, J Naidoo, BD Santomasso… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To increase awareness, outline strategies, and offer guidance on the
recommended management of immune-related adverse events (irAEs) in patients treated …

Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

J Haanen, M Obeid, L Spain, F Carbonnel… - Annals of …, 2022 - annalsofoncology.org
Adverse events (AEs) related to the use of immune checkpoint inhibitor (ICI) therapy are
defined as immune-related (IR) AEs (irAEs). irAEs are graded according to the Common …

Immunotherapy in hematologic malignancies: achievements, challenges and future prospects

L Tang, Z Huang, H Mei, Y Hu - Signal Transduction and Targeted …, 2023 - nature.com
The immune-cell origin of hematologic malignancies provides a unique avenue for the
understanding of both the mechanisms of immune responsiveness and immune escape …

Epidemiology and risk factors for the development of cutaneous toxicities in patients treated with immune-checkpoint inhibitors: a United States population-level …

S Wongvibulsin, V Pahalyants, M Kalinich… - Journal of the American …, 2022 - Elsevier
Background A variety of dermatoses have been reported in the growing number of patients
treated with immune-checkpoint inhibitors (ICIs), but the current understanding of cutaneous …

Cutaneous manifestations associated with immune checkpoint inhibitors

T Watanabe, Y Yamaguchi - Frontiers in Immunology, 2023 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block key mediators of
tumor-mediated immune evasion. The frequency of its use has increased rapidly and has …

Dermatologic toxicities to immune checkpoint inhibitor therapy: A review of histopathologic features

SR Ellis, AT Vierra, JW Millsop, ME Lacouture… - Journal of the American …, 2020 - Elsevier
Antineoplastic agents that use the immune system have revolutionized cancer treatment.
Specifically, implementation of immune checkpoint inhibitors, monoclonal antibodies that …

European recommendations for management of immune checkpoint inhibitors‐derived dermatologic adverse events. The EADV task force 'Dermatology for cancer …

Z Apalla, V Nikolaou, D Fattore… - Journal of the …, 2022 - Wiley Online Library
The introduction of immune checkpoint inhibitors (ICIs) opened a new era in oncologic
therapy. The favourable profile of ICIs in terms of efficacy and safety can be overshadowed …

Checkpoint inhibitor immune-related adverse events: A focused review on autoantibodies and B cells as biomarkers, advancements and future possibilities

J Taylor, A Gandhi, E Gray, P Zaenker - Frontiers in immunology, 2023 - frontiersin.org
The use of immune checkpoint inhibitors (ICIs) has evolved rapidly with unprecedented
treatment benefits being obtained for cancer patients, including improved patient survival …