The computational anatomy of psychosis

RA Adams, KE Stephan, HR Brown, CD Frith… - Frontiers in …, 2013 - frontiersin.org
This paper considers psychotic symptoms in terms of false inferences or beliefs. It is based
on the notion that the brain is an inference machine that actively constructs hypotheses to …

Whatever next? Predictive brains, situated agents, and the future of cognitive science

A Clark - Behavioral and brain sciences, 2013 - cambridge.org
Brains, it has recently been argued, are essentially prediction machines. They are bundles
of cells that support perception and action by constantly attempting to match incoming …

Advances in the computational understanding of mental illness

QJM Huys, M Browning, MP Paulus… - …, 2021 - nature.com
Computational psychiatry is a rapidly growing field attempting to translate advances in
computational neuroscience and machine learning into improved outcomes for patients …

Early-stage visual perception impairment in schizophrenia, bottom-up and back again

P Adámek, V Langová, J Horáček - Schizophrenia, 2022 - nature.com
Visual perception is one of the basic tools for exploring the world. However, in
schizophrenia, this modality is disrupted. So far, there has been no clear answer as to …

[HTML][HTML] A perceptual inference mechanism for hallucinations linked to striatal dopamine

CM Cassidy, PD Balsam, JJ Weinstein, RJ Rosengard… - Current Biology, 2018 - cell.com
Hallucinations, a cardinal feature of psychotic disorders such as schizophrenia, are known
to depend on excessive striatal dopamine. However, an underlying cognitive mechanism …

[HTML][HTML] Schizophrenia and the eye

SM Silverstein, R Rosen - Schizophrenia Research: Cognition, 2015 - Elsevier
Although visual processing impairments are common in schizophrenia, it is not clear to what
extent these originate in the eye vs. the brain. This review highlights potential contributions …

Predictive waves in the autism-schizophrenia continuum: a novel biobehavioral model

L Tarasi, J Trajkovic, S Diciotti, G di Pellegrino… - Neuroscience & …, 2022 - Elsevier
The brain is a predictive machine. Converging data suggests a diametric predictive strategy
from autism spectrum disorders (ASD) to schizophrenic spectrum disorders (SSD). Whereas …

What visual illusions teach us about schizophrenia

CE Notredame, D Pins, S Deneve… - Frontiers in integrative …, 2014 - frontiersin.org
Illusion, namely a mismatch between the objective and perceived properties of an object
present in the environment, is a common feature of visual perception, both in normal and …

[HTML][HTML] Computational neuroimaging strategies for single patient predictions

KE Stephan, F Schlagenhauf, QJM Huys, S Raman… - Neuroimage, 2017 - Elsevier
Neuroimaging increasingly exploits machine learning techniques in an attempt to achieve
clinically relevant single-subject predictions. An alternative to machine learning, which tries …

Translational perspectives for computational neuroimaging

KE Stephan, S Iglesias, J Heinzle, AO Diaconescu - Neuron, 2015 - cell.com
Functional neuroimaging has made fundamental contributions to our understanding of brain
function. It remains challenging, however, to translate these advances into diagnostic tools …