Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action

R Mani, V Natesan - Phytochemistry, 2018 - Elsevier
In recent years, public and scientific interest in plant flavonoids has tremendously increased
because of their postulated health benefits. This review was mainly focuses on the flavone …

Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives

ER Kasala, LN Bodduluru, RM Madana, R Gogoi… - Toxicology letters, 2015 - Elsevier
Chrysin, a naturally occurring flavone, abundantly found in numerous plant extracts
including propolis and in honey is one of the most widely used herbal medicine in Asian …

Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview

PK Teja, J Mithiya, AS Kate, K Bairwa, SK Chauthe - Phytomedicine, 2022 - Elsevier
Abstract Background Herbal Nano Medicines (HNMs) are nano-sized medicine containing
herbal drugs as extracts, enriched fractions or biomarker constituents. HNMs have certain …

[HTML][HTML] An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Neurological diseases are responsible for a large number of morbidities and mortalities in
the world. Flavonoids are phytochemicals that possess various health-promoting impacts …

[HTML][HTML] Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin

M Talebi, M Talebi, T Farkhondeh… - Cancer Cell …, 2021 - Springer
Chrysin has been shown to exert several beneficial pharmacological activities. Chrysin has
anti-cancer, anti-viral, anti-diabetic, neuroprotective, cardioprotective, hepatoprotective, and …

Preparation and characterization of PLGA-PEG-PLGA polymeric nanoparticles for co-delivery of 5-Fluorouracil and Chrysin

S Khaledi, S Jafari, S Hamidi, O Molavi… - Journal of Biomaterials …, 2020 - Taylor & Francis
Despite significant advances in cancer therapy, chemotherapeutic agents are still the main
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …

Terminal modification of polymeric micelles with π-conjugated moieties for efficient anticancer drug delivery

Y Liang, X Deng, L Zhang, X Peng, W Gao, J Cao, Z Gu… - Biomaterials, 2015 - Elsevier
High drug loading content is the critical factor to polymeric micelles for efficient
chemotherapy. Small molecules of cinnamic acid, 7-carboxymethoxy coumarin and chrysin …

Long‐circulating drug‐dye‐based micelles with ultrahigh pH‐sensitivity for deep tumor penetration and superior chemo‐photothermal therapy

C Song, Y Li, T Li, Y Yang, Z Huang… - Advanced Functional …, 2020 - Wiley Online Library
Nanocarriers for chemo‐photothermal therapy suffer from insufficient retention at the tumor
site and poor penetration into tumor parenchyma. A smart drug‐dye‐based micelle is …

Improving anticancer activity of chrysin using tumor microenvironment pH-responsive and self-assembled nanoparticles

AK Jangid, R Solanki, S Patel, K Medicherla… - ACS …, 2022 - ACS Publications
Chrysin is a natural bioactive compound with potential biological activities. However,
unfavorable physicochemical properties of native chrysin make it difficult to achieve good …

[HTML][HTML] Chrysin-Loaded Chitosan Nanoparticles Potentiates Antibiofilm Activity against Staphylococcus aureus

B Siddhardha, U Pandey, K Kaviyarasu, R Pala… - Pathogens, 2020 - mdpi.com
The application of nanotechnology in medicine is gaining popularity due to its ability to
increase the bioavailability and biosorption of numerous drugs. Chrysin, a flavone …