Molecular subtyping of cancer: current status and moving toward clinical applications

L Zhao, VHF Lee, MK Ng, H Yan… - Briefings in …, 2019 - academic.oup.com
Cancer is a collection of genetic diseases, with large phenotypic differences and genetic
heterogeneity between different types of cancers and even within the same cancer type …

Missing value imputation for gene expression data: computational techniques to recover missing data from available information

AWC Liew, NF Law, H Yan - Briefings in bioinformatics, 2011 - academic.oup.com
Microarray gene expression data generally suffers from missing value problem due to a
variety of experimental reasons. Since the missing data points can adversely affect …

FABIA: factor analysis for bicluster acquisition

S Hochreiter, U Bodenhofer, M Heusel, A Mayr… - …, 2010 - academic.oup.com
Motivation: Biclustering of transcriptomic data groups genes and samples simultaneously. It
is emerging as a standard tool for extracting knowledge from gene expression …

Gene expression profiling of 1200 pancreatic ductal adenocarcinoma reveals novel subtypes

L Zhao, H Zhao, H Yan - BMC cancer, 2018 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of
cancer related death in the world with a five-year survival rate of less than 5%. Not all PDAC …

FleBiC: Learning classifiers from high-dimensional biomedical data using discriminative biclusters with non-constant patterns

R Henriques, SC Madeira - Pattern Recognition, 2021 - Elsevier
The discovery of discriminative patterns from high-dimensional data offers the possibility to
learn from informative subspaces and pattern-centric features, paving the way to associative …

Quality measures for gene expression biclusters

B Pontes, R Girldez, JS Aguilar-Ruiz - PloS one, 2015 - journals.plos.org
An noticeable number of biclustering approaches have been proposed proposed for the
study of gene expression data, especially for discovering functionally related gene sets …

Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate visualization

KO Cheng, NF Law, WC Siu, AWC Liew - BMC bioinformatics, 2008 - Springer
Background The DNA microarray technology allows the measurement of expression levels
of thousands of genes under tens/hundreds of different conditions. In microarray data, genes …

Finding correlated biclusters from gene expression data

WH Yang, DQ Dai, H Yan - IEEE Transactions on Knowledge …, 2010 - ieeexplore.ieee.org
Extracting biologically relevant information from DNA microarrays is a very important task for
drug development and test, function annotation, and cancer diagnosis. Various clustering …

Biclustering of gene expression data by correlation-based scatter search

JA Nepomuceno, A Troncoso, JS Aguilar-Ruiz - BioData mining, 2011 - Springer
Background The analysis of data generated by microarray technology is very useful to
understand how the genetic information becomes functional gene products. Biclustering …

Evolutionary optimized fuzzy reasoning with mined diagnostic patterns for classification of breast tumors in ultrasound

Q Huang, B Hu, F Zhang - Information Sciences, 2019 - Elsevier
Abstract Computer-aided-diagnostic (CAD) techniques are of great help in facilitating the
diagnosis of breast ultrasound (BUS) images. Conventional CAD approaches segment the …