There has been an escalation in reports over the last decade examining the efficacy of bone
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …

Since the identification in 1988 of bone morphogenetic protein 2 (BMP2) as a potent inducer
of bone and cartilage formation, BMP superfamily signalling has become one of the most …

Highlights•Alternative bone regenerative therapeutics are needed.•Ions have been
proposed to regenerate skeletal tissue.•Drug delivery systems have been studied to deliver …

Periodontal disease is categorized by the destruction of periodontal tissues. Over the years,
there have been several clinical techniques and material options that been investigated for …

Regenerative engineering converges tissue engineering, advanced materials science, stem
cell science, and developmental biology to regenerate complex tissues such as whole limbs …

Repair and regeneration of human tissues and organs using biomaterials, cells, and/or
growth factors is a great challenge for tissue engineers and surgeons. The convergence of …

Growth factors (GFs) are critical in tissue repair, but their translation to clinical use has been
modest. Physiologically, GF interactions with extracellular matrix (ECM) components …

Bone morphogenetic proteins (BMPs) are responsible for bone formation during
embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs …

Background Fractures of the proximal humerus, often termed shoulder fractures, are
common injuries, especially in older people. The management of these fractures varies …

Scaffolds functionalized with bone morphogenetic protein-2 (BMP-2) have shown great
potential for bone regeneration. However, structural instability and the necessity for supra …