Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

FungiDB: an integrated bioinformatic resource for fungi and oomycetes

EY Basenko, JA Pulman, A Shanmugasundram… - Journal of Fungi, 2018 - mdpi.com
FungiDB (fungidb. org) is a free online resource for data mining and functional genomics
analysis for fungal and oomycete species. FungiDB is part of the Eukaryotic Pathogen …

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

B Amos, C Aurrecoechea, M Barba… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB,
https://veupathdb. org) represents the 2019 merger of VectorBase with the EuPathDB …

Ensembl Genomes 2022: an expanding genome resource for non-vertebrates

AD Yates, J Allen, RM Amode, AG Azov… - Nucleic acids …, 2022 - academic.oup.com
Abstract Ensembl Genomes (https://www. ensemblgenomes. org) provides access to non-
vertebrate genomes and analysis complementing vertebrate resources developed by the …

The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA …

JF Armstrong, E Faccenda, SD Harding… - Nucleic acids …, 2020 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (www. guidetopharmacology. org) is
an open-access, expert-curated database of molecular interactions between ligands and …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites

AJ Reid, AM Talman, HM Bennett, AR Gomes… - elife, 2018 - elifesciences.org
Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …

A resource for improved predictions of Trypanosoma and Leishmania protein three-dimensional structure

RJ Wheeler - PLoS One, 2021 - journals.plos.org
AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

ApiAP2 transcription factors in apicomplexan parasites

MD Jeninga, JE Quinn, M Petter - Pathogens, 2019 - mdpi.com
Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …

Multiple independent origins of apicomplexan-like parasites

V Mathur, M Kolísko, E Hehenberger, NAT Irwin… - Current Biology, 2019 - cell.com
The apicomplexans are a group of obligate animal pathogens that include Plasmodium
(malaria), Toxoplasma (toxoplasmosis), and Cryptosporidium (cryptosporidiosis)[1]. They …