It has been known for a long time that thyroid hormones have prominent effects on hepatic
fatty acid and cholesterol synthesis and metabolism. Indeed, hypothyroidism has been …

Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Background: Thyroid hormones (THs) exert a strong influence on mammalian lipid
metabolism at the systemic and hepatic levels by virtue of their roles in regulating circulating …

Thyroid hormones have long been known to have a range of effects on the cardiovascular
system. However, significant knowledge gaps exist concerning the precise molecular and …

Hypothyroidism is closely associated with increased serum total cholesterol (TC), low-
density lipoprotein cholesterol (LDL-C) and triglyceride (TG). The thyroid gland plays an …

Thyroid hormone (TH) plays a critical role in maintaining metabolic homeostasis throughout
life. It is well known that the liver and thyroid are intimately linked, with TH playing important …

Thyroid hormones (THs) are secreted by the thyroid gland. They control lipid, carbohydrate,
and protein metabolism, heart rate, neural development, as well as cardiovascular, renal …

For over 100 years, thyroid hormones have been known to be essential for neonatal
neurodevelopment but whether they are required by the foetal brain remains a matter of …

Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

Thyroid hormones regulate cholesterol and lipoprotein metabolism, whereas thyroid
disorders, including overt and subclinical hypothyroidism (SCH), considerably alter lipid …