Fusarium is a species-rich group of mycotoxigenic plant pathogens that ranks as one of the
most economically important fungal genera in the world. During growth and infection, they …

Mammalian TIP60 is a multi-functional enzyme with histone acetylation and histone dimer
exchange activities. It plays roles in diverse cellular processes including transcription, DNA …

Chromatin remodeling plays a key role in the establishment and maintenance of gene
expression patterns essential for plant development and responses to environmental factors …

Deoxyribonucleic acid in eukaryotes wraps around the histone octamer to form
nucleosomes 1, the fundamental unit of chromatin. The N termini of histone H4 interact with …

The human nucleosome acetyltransferase of histone H4 (NuA4)/Tat-interactive protein, 60
kilodalton (TIP60) coactivator complex, a fusion of the yeast switch/sucrose nonfermentable …

Histone acetylation regulates most DNA transactions and is dynamically controlled by highly
conserved enzymes. The only essential histone acetyltransferase (HAT) in yeast, Esa1, is …

The NuA4 protein complex acetylates histones H4 and H2A to activate both transcription
and DNA repair. We report the 3.1-Å resolution cryo-electron microscopy structure of the …

Histones are subject to a diverse array of post-translational modifications. Among them,
lysine acetylation is not only the most pervasive and dynamic modification but also highly …

Abstract MRG15/MORF4L1 is a highly conserved protein in eukaryotes that contains a
chromodomain (CHD) recognizing methylation of lysine 36 on histone H3 (H3K36me3) in …

Chromosomal translocations frequently promote carcinogenesis by producing gain-of-
function fusion proteins. Recent studies have identified highly recurrent chromosomal …