During aging, the cellular milieu of the brain exhibits tell-tale signs of compromised bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network …
J Silva dos Santos, JP Goncalves Cirino… - Frontiers in …, 2021 - frontiersin.org
Kaempferol (KPF) is a flavonoid antioxidant found in fruits and vegetables. Many studies have described the beneficial effects of dietary KPF in reducing the risk of chronic diseases …
Alzheimer's disease (AD) is considered a polygenic disorder. This view is clouded, however, by lingering uncertainty over how to treat the quasi" monogenic" role of apolipoprotein E …
R Wehbe, J Frangieh, M Rima, D El Obeid, JM Sabatier… - Molecules, 2019 - mdpi.com
Apitherapy is an alternate therapy that relies on the usage of honeybee products, most importantly bee venom for the treatment of many human diseases. The venom can be …
Glutathione transferase classical GSH conjugation activity plays a critical role in cellular detoxification against xenobiotics and noxious compounds as well as against oxidative …
MA DeTure, DW Dickson - Molecular neurodegeneration, 2019 - Springer
Alzheimer's disease is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline, although less common clinical presentations are …
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
KA Jellinger, AD Korczyn - BMC medicine, 2018 - Springer
Abstract Background Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), which share many clinical, neurochemical, and morphological features, have been …
Dynamic functional connectivity captures temporal variations of functional connectivity during MRI acquisition and it may be a suitable method to detect cognitive changes in …