As major components of innate immunity, NK cells not only exert cell-mediated cytotoxicity
against tumor cells or infected cells, but also act to regulate the function of other immune …

Increasing evidences have pointed out the relevance of natural killer (NK) cells in organ-
specific and systemic autoimmune diseases. NK cells bear a plethora of activating and …

The pathogenetic mechanisms responsible for the induction of immune‐mediated disorders,
such as psoriasis, remain not well characterized. Molecular signaling pathways are not well …

Synapses are increasingly recognized as key structures that malfunction in disorders like
schizophrenia, mental retardation, and neurodegenerative diseases. The importance and …

IL-10 involvement in disease progression continues to be evaluated. Through these studies
it has become evident that the role of IL-10 in immunological conditions encompasses a …

Background Pemphigus vulgaris (PV) is a typical autoimmune disease caused by
autoantibodies. Innate lymphoid cells (ILCs) are non-antigen-dependent populations …

Psoriasis vulgaris is a chronic inflammatory disease of the skin with a strong genetic
component and immune system involvement. Although some evidence suggests that …

p38 mitogen activated protein kinase (p38 MAPK) signaling plays a major role in the
modulation of immune‐mediated inflammatory responses and therefore has been linked …

Relapsing-remitting multiple sclerosis (RRMS) and myelin oligodendrocyte glycoprotein
(MOG) antibody-associated disease (MOGAD) are inflammatory demyelinating diseases of …

Pemphigus, a potentially lethal autoimmune skin disease, is mediated by desmoglein-
specific antibodies, manifesting cutaneous and mucosal blisters and erosions. The …