Exosomes as mediators of intercellular crosstalk in metabolism

R Isaac, FCG Reis, W Ying, JM Olefsky - Cell metabolism, 2021 - cell.com
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …

Chitosan: A review of molecular structure, bioactivities and interactions with the human body and micro-organisms

SG Kou, L Peters, M Mucalo - Carbohydrate Polymers, 2022 - Elsevier
Chitosan has many desirable attributes eg antimicrobial properties and promoting wound
healing, and is used in various applications. This article first discusses how degree of …

[HTML][HTML] New insights into the mechanisms of pulmonary edema in acute lung injury

R Herrero, G Sanchez, JA Lorente - Annals of Translational …, 2018 - ncbi.nlm.nih.gov
Appearance of alveolar protein-rich edema is an early event in the development of acute
respiratory distress syndrome (ARDS). Alveolar edema in ARDS results from a significant …

Extracellular vesicles: novel communicators in lung diseases

A Mohan, S Agarwal, M Clauss, NS Britt… - Respiratory research, 2020 - Springer
The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

High-mobility group box 1 (HMGB1) in COVID-19: extrapolation of dangerous liaisons

HM Al-Kuraishy, AI Al-Gareeb, L Alkazmi… - …, 2022 - Springer
High-mobility group box 1 (HMGB1), a multifunctional nuclear protein, exists mainly within
the nucleus of all mammal eukaryotic cells. It is actively secreted by the necrotic cells as a …

An evolving new paradigm: endothelial cells–conditional innate immune cells

J Mai, A Virtue, J Shen, H Wang, XF Yang - Journal of hematology & …, 2013 - Springer
Endothelial cells (ECs) are a heterogeneous population that fulfills many physiological
processes. ECs also actively participate in both innate and adaptive immune responses …

Microparticles: biomarkers and beyond

D Burger, S Schock, CS Thompson… - Clinical …, 2013 - portlandpress.com
Membrane microparticles are submicron fragments of membrane shed into extracellular
space from cells under conditions of stress/injury. They may be distinguished from other …

Alveolar macrophage-derived microvesicles mediate acute lung injury

S Soni, MR Wilson, KP O'Dea, M Yoshida, U Katbeh… - Thorax, 2016 - thorax.bmj.com
Background Microvesicles (MVs) are important mediators of intercellular communication,
packaging a variety of molecular cargo. They have been implicated in the pathophysiology …

Red blood cell extracellular vesicle-based drug delivery: challenges and opportunities

W Chiangjong, P Netsirisawan, S Hongeng… - Frontiers in …, 2021 - frontiersin.org
Recently, red blood cell-derived extracellular vesicles (RBCEVs) have attracted attention for
clinical applications because of their safety and biocompatibility. RBCEVs can escape …

Endothelial extracellular vesicles—promises and challenges

C Hromada, S Mühleder, J Grillari, H Redl… - Frontiers in …, 2017 - frontiersin.org
Extracellular vesicles, including exosomes, microparticles, and apoptotic bodies, are
phospholipid bilayer-enclosed vesicles that have once been considered as cell debris …