Cornification of keratinocytes is associated with differential changes in the catalytic activity and the immunoreactivity of transglutaminase-1
M Surbek, T Van de Steene, AP Sachslehner… - Scientific Reports, 2023 - nature.com
Abstract Transglutaminase 1 (TGM1) plays an essential role in skin barrier formation by
cross-linking proteins in differentiated keratinocytes. Here, we established a protocol for the …
cross-linking proteins in differentiated keratinocytes. Here, we established a protocol for the …
Transglutaminase activity is conserved in stratified epithelia and skin appendages of mammals and birds
AP Sachslehner, M Surbek, B Golabi… - International Journal of …, 2023 - mdpi.com
The cross-linking of structural proteins is critical for establishing the mechanical stability of
the epithelial compartments of the skin and skin appendages. The introduction of isopeptide …
the epithelial compartments of the skin and skin appendages. The introduction of isopeptide …
The evolution of transglutaminases underlies the origin and loss of cornified skin appendages in vertebrates
AP Sachslehner, M Surbek, KB Holthaus… - Molecular Biology …, 2024 - academic.oup.com
Transglutaminases (TGMs) cross-link proteins by introducing covalent bonds between
glutamine and lysine residues. These cross-links are essential for epithelial cornification …
glutamine and lysine residues. These cross-links are essential for epithelial cornification …
The diverse major histocompatibility complex haplotypes of a common commercial chicken line and their effect on marek's disease virus pathogenesis and …
LD Bertzbach, CA Tregaskes, RJ Martin… - Frontiers in …, 2022 - frontiersin.org
The major histocompatibility complex (MHC) is crucial for appropriate immune responses
against invading pathogens. Chickens possess a single predominantly-expressed class I …
against invading pathogens. Chickens possess a single predominantly-expressed class I …
Heme oxygenase-1 is upregulated during differentiation of keratinocytes but its expression is dispensable for cornification of murine epidermis
M Surbek, S Sukseree, AP Sachslehner… - Journal of …, 2023 - mdpi.com
The epidermal barrier of mammals is initially formed during embryonic development and
continuously regenerated by the differentiation and cornification of keratinocytes in postnatal …
continuously regenerated by the differentiation and cornification of keratinocytes in postnatal …
[PDF][PDF] The Diverse Major Histocompatibility Complex Haplotypes of a Common Commercial Chicken Line and Their Effect on Marek's Disease Virus Pathogenesis …
LD Bertzbach, CA Tregaskes, RJ Martin, US Deumer… - 2022 - researchgate.net
The major histocompatibility complex (MHC) is crucial for appropriate immune responses
against invading pathogens. Chickens possess a single predominantly-expressed class I …
against invading pathogens. Chickens possess a single predominantly-expressed class I …