The microbial ecology of Escherichia coli in the vertebrate gut

E Foster-Nyarko, MJ Pallen - FEMS microbiology reviews, 2022 - academic.oup.com
Escherichia coli has a rich history as biology's 'rock star', driving advances across many
fields. In the wild, E. coli resides innocuously in the gut of humans and animals but is also a …

Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment

S Whelan, B Lucey, K Finn - Microorganisms, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections, especially
among women and older adults, leading to a significant global healthcare cost burden …

Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes

BJ Russell, SD Brown, N Siguenza, I Mai, AR Saran… - Cell, 2022 - cell.com
Live bacterial therapeutics (LBTs) could reverse diseases by engrafting in the gut and
providing persistent beneficial functions in the host. However, attempts to functionally …

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli

M Touchon, A Perrin, JAM De Sousa, B Vangchhia… - PLoS …, 2020 - journals.plos.org
Escherichia coli is mostly a commensal of birds and mammals, including humans, where it
can act as an opportunistic pathogen. It is also found in water and sediments. We …

Gut microbiome perturbation, antibiotic resistance, and Escherichia coli strain dynamics associated with international travel: a metagenomic analysis

CJ Worby, S Sridhar, SE Turbett, MV Becker… - The Lancet …, 2023 - thelancet.com
Background Culture-based studies have shown that acquisition of extended-spectrum β-
lactamase-producing Enterobacterales is common during international travel; however, little …

Comprehensive Genomic Investigation of Tigecycline Resistance Gene tet(X4)-Bearing Strains Expanding among Different Settings

R Li, Y Li, K Peng, Y Yin, Y Liu, T He, L Bai… - Microbiology …, 2021 - Am Soc Microbiol
The emergence of plasmid-mediated tigecycline resistance genes has attracted a great deal
of attention globally. Currently, no comprehensive in-depth genomic epidemiology study of …

Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal cancer

M Oliero, R Hajjar, T Cuisiniere, G Fragoso, A Calvé… - Gut Pathogens, 2022 - Springer
Background Colorectal cancer (CRC) is the third most diagnosed cancer and the second
most common cause of cancer deaths worldwide. CRC patients present with an increase in …

Genomic insights into virulence, antimicrobial resistance, and adaptation acumen of Escherichia coli isolated from an urban environment

P Saini, V Bandsode, A Singh, SK Mendem, T Semmler… - Mbio, 2024 - Am Soc Microbiol
Populations of common commensal bacteria such as Escherichia coli undergo genetic
changes by the acquisition of certain virulence and antimicrobial resistance (AMR) encoding …

To kill or to be killed: pangenome analysis of Escherichia coli strains reveals a tailocin specific for pandemic ST131

E Tantoso, B Eisenhaber, M Kirsch, V Shitov, Z Zhao… - Bmc Biology, 2022 - Springer
Background Escherichia coli (E. coli) has been one of the most studied model organisms in
the history of life sciences. Initially thought just to be commensal bacteria, E. coli has shown …

Evidence for Widespread Class II Microcins in Enterobacterales Genomes

TJ Cole, JK Parker, AL Feller, CO Wilke… - Applied and …, 2022 - Am Soc Microbiol
Microcins are a class of antimicrobial peptides produced by certain Gram-negative bacterial
species to kill or inhibit the growth of competing bacteria. Only 10 unique, experimentally …