Maladaptive plasticity in tinnitus—triggers, mechanisms and treatment

SE Shore, LE Roberts, B Langguth - Nature Reviews Neurology, 2016 - nature.com
Tinnitus is a phantom auditory sensation that reduces quality of life for millions of people
worldwide, and for which there is no medical cure. Most cases of tinnitus are associated with …

[HTML][HTML] Tinnitus: does gain explain?

W Sedley - Neuroscience, 2019 - Elsevier
Many, or most, tinnitus models rely on increased central gain in the auditory pathway as all
or part of the explanation, in that central auditory neurones deprived of their usual sensory …

Evidence that hidden hearing loss underlies amplitude modulation encoding deficits in individuals with and without tinnitus

BT Paul, IC Bruce, LE Roberts - Hearing Research, 2017 - Elsevier
Damage to auditory nerve fibers that expresses with suprathreshold sounds but is hidden
from the audiogram has been proposed to underlie deficits in temporal coding ability …

Rationale and efficacy of sound therapies for tinnitus and hyperacusis

M Pienkowski - Neuroscience, 2019 - Elsevier
Sound therapies are a common component of treatments for tinnitus and hyperacusis. The
original idea was to partially or completely mask tinnitus with broadband noise delivered by …

Impairments of speech comprehension in patients with tinnitus—a review

D Ivansic, O Guntinas-Lichius, B Müller… - Frontiers in aging …, 2017 - frontiersin.org
Tinnitus describes the subjective perception of a sound despite the absence of external
stimulation. Being a sensory symptom the majority of studies focusses on the auditory …

[HTML][HTML] Residual inhibition: From the putative mechanisms to potential tinnitus treatment

AV Galazyuk, RJ Longenecker, SV Voytenko… - Hearing research, 2019 - Elsevier
Neurons in various sensory systems show some level of spontaneous firing in the absence
of sensory stimuli. In the auditory system spontaneous firing has been shown at all levels of …

Unintended consequences of white noise therapy for tinnitus—otolaryngology's cobra effect: a review

M Attarha, J Bigelow… - … Otolaryngology–Head & …, 2018 - jamanetwork.com
Importance Critical to the success of many medical therapeutics is a consideration of the
brain's miraculous ability to dynamically rewire itself anatomically and neurochemically on …

Long-lasting forward suppression of spontaneous firing in auditory neurons: implication to the residual inhibition of tinnitus

AV Galazyuk, SV Voytenko, RJ Longenecker - Journal of the Association …, 2017 - Springer
Tinnitus is the perception of a sound that has no external source. Sound stimuli can
suppress spontaneous firing in auditory neurons long after stimulus offset. It is unknown how …

Eavesdropping on Tinnitus Using MEG: Lessons Learned and Future Perspectives

L Reisinger, G Demarchi, N Weisz - … of the Association for Research in …, 2023 - Springer
Tinnitus has been widely investigated in order to draw conclusions about the underlying
causes and altered neural activity in various brain regions. Existing studies have based their …

Auditory evoked responses in older adults with normal hearing, untreated, and treated age-related hearing loss

KS McClannahan, KC Backer, KL Tremblay - Ear and hearing, 2019 - journals.lww.com
Objectives: The goal of this study was to identify the effects of auditory deprivation (age-
related hearing loss) and auditory stimulation (history of hearing aid use) on the neural …