Going beyond primary motor cortex to improve brain–computer interfaces

JA Gallego, TR Makin, SD McDougle - Trends in neurosciences, 2022 - cell.com
Brain–computer interfaces (BCIs) for movement restoration typically decode the user's intent
from neural activity in their primary motor cortex (M1) and use this information to enable …

On closed-loop brain stimulation systems for improving the quality of life of patients with neurological disorders

AN Belkacem, N Jamil, S Khalid… - Frontiers in human …, 2023 - frontiersin.org
Emerging brain technologies have significantly transformed human life in recent decades.
For instance, the closed-loop brain-computer interface (BCI) is an advanced software …

Striatal activity topographically reflects cortical activity

AJ Peters, JMJ Fabre, NA Steinmetz, KD Harris… - Nature, 2021 - nature.com
The cortex projects to the dorsal striatum topographically, to regulate behaviour,–, but
spiking activity in the two structures has previously been reported to have markedly different …

Neural plasticity in sensorimotor brain–machine interfaces

MC Dadarlat, RA Canfield… - Annual review of …, 2023 - annualreviews.org
Brain–machine interfaces (BMIs) aim to treat sensorimotor neurological disorders by
creating artificial motor and/or sensory pathways. Introducing artificial pathways creates new …

Neural reinforcement: re-entering and refining neural dynamics leading to desirable outcomes

VR Athalye, JM Carmena, RM Costa - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Behavioral reinforcement is neural reinforcement.•We propose a framework
where reinforcement acts on neural population dynamics with different time courses.• …

Integrating the roles of midbrain dopamine circuits in behavior and neuropsychiatric disease

APF Chen, L Chen, TA Kim, Q Xiong - Biomedicines, 2021 - mdpi.com
Dopamine (DA) is a behaviorally and clinically diverse neuromodulator that controls CNS
function. DA plays major roles in many behaviors including locomotion, learning, habit …

The complex affective and cognitive capacities of rats

I Ben-Ami Bartal - Science, 2024 - science.org
For several decades, although studies of rat physiology and behavior have abounded,
research on rat emotions has been limited in scope to fear, anxiety, and pain. Converging …

Dendritic Mechanisms for In Vivo Neural Computations and Behavior

L Fischer, RM Soto-Albors, VD Tang… - Journal of …, 2022 - Soc Neuroscience
Dendrites receive the vast majority of a single neuron's inputs, and coordinate the
transformation of these signals into neuronal output. Ex vivo and theoretical evidence has …

Reinforcement learning links spontaneous cortical dopamine impulses to reward

C Foo, A Lozada, J Aljadeff, Y Li, JW Wang… - Current Biology, 2021 - cell.com
In their pioneering study on dopamine release, Romo and Schultz speculated"... that the
amount of dopamine released by unmodulated spontaneous impulse activity exerts a tonic …

Clinical neuroscience and neurotechnology: An amazing symbiosis

A Cometa, A Falasconi, M Biasizzo, J Carpaneto… - Iscience, 2022 - cell.com
In the last decades, clinical neuroscience found a novel ally in neurotechnologies, devices
able to record and stimulate electrical activity in the nervous system. These technologies …