Growth factor engineering strategies for regenerative medicine applications

X Ren, M Zhao, B Lash, MM Martino… - … in bioengineering and …, 2020 - frontiersin.org
Growth factors are critical molecules for tissue repair and regeneration. Therefore,
recombinant growth factors have raised a lot of hope for regenerative medicine applications …

Managing diabetic foot ulcers: pharmacotherapy for wound healing

D Dixon, M Edmonds - Drugs, 2021 - Springer
Historically, there has been a scarcity of evidence-based topical therapy to hasten the
healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged …

Advances in drug delivery systems (DDSs) to release growth factors for wound healing and skin regeneration

G Gainza, S Villullas, JL Pedraz, RM Hernandez… - … , Biology and Medicine, 2015 - Elsevier
Current advances in novel drug delivery systems (DDSs) to release growth factors (GFs)
represent a great opportunity to develop new therapies or enhance the effectiveness of …

Therapeutic advances in wound healing

A Oliveira, S Simões, A Ascenso… - Journal of Dermatological …, 2022 - Taylor & Francis
Wound healing is a complex physiological process that occurs in the human body involving
the sequential activation of multiple cell types and signaling pathways in a coordinated …

[PDF][PDF] Growth factors in wound healing—a review

L Vaidyanathan - Biomed Pharmacol J, 2021 - academia.edu
The review is an overview of the features of growth factors involved in cellular signaling
mechanisms regulating the wound healing process. Understanding the insights of this …

Nanocarrier-mediated topical insulin delivery for wound healing

AS Macedo, F Mendes, P Filipe, S Reis, P Fonte - Materials, 2021 - mdpi.com
Wound care has been clinically demanding due to inefficacious treatment that represents an
economic burden for healthcare systems. In Europe, approximately 7 million people are …

Keratinocyte Migration in a Three-Dimensional In Vitro Wound Healing Model Co-Cultured with Fibroblasts

K Iyer, Z Chen, T Ganapa, BM Wu, B Tawil… - Tissue engineering and …, 2018 - Springer
Abstract Background: Because three-dimensional (3D) models more closely mimic native
tissues, one of the goals of 3D in vitro tissue models is to aid in the development and toxicity …

Preparation and in vitro evaluation of FGF-2 incorporated carboxymethyl chitosan nanoparticles

CT Nguyen, TT Nguyen, TT Nguyen, PPT Nguyen… - Carbohydrate …, 2017 - Elsevier
Abstract Fibroblast growth factor 2 (FGF-2) is a multi-functional protein involving in wound
healing. However, FGF-2 is easily degradable in vivo, which limited its use for wound …

Human recombinant epidermal growth factor in skin lesions: 77 cases in EPItelizando project

J Esquirol-Caussa, E Herrero-Vila - Journal of Dermatological …, 2019 - Taylor & Francis
Objective: To analyze compounded recombinant human epidermal growth factor (rhEGF)
effectiveness on skin lesions through a case series. Design: Multicentric series of skin …

Prevention of tooth extraction-triggered bisphosphonate-related osteonecrosis of the jaws with basic fibroblast growth factor: An experimental study in rats

M Imada, T Yagyuu, Y Ueyama, M Maeda… - PLoS …, 2019 - journals.plos.org
Osteonecrosis of the jaw induced by administration of bisphosphonates (BPs), BP-related
osteonecrosis (BRONJ), typically develops after tooth extraction and is medically …