Remodeling of the myocardium is the major mechanism for disability and death in prevalent
cardiovascular diseases such as hypertension, heart failure and myocardial infarction (MI). It …

Hypertrophic scars and keloids are 2 forms of excessive cutaneous scarring that occur in
predisposed individuals. The healing process varies greatly among patients, and the risk of …

Osteopontin (OPN), an extracellular matrix protein, is expressed in the myocardium with
hypertrophy and failure. We tested the hypothesis that OPN plays a role in left ventricular …

Background—The molecular pathways that control the wound healing after myocardial
infarction (MI) are not completely elucidated. One of these pathways is the Wnt/Frizzled …

Background: Angiotensin-converting enzyme inhibitors are widely used in medicine
because of their antihypertensive and antifibrogenic effects. Angiotensin-converting enzyme …

Objectives: We sought to determine whether reperfusion and the calcium channel blocker
amlodipine or the angiotensin-converting enzyme inhibitor enalapril, during healing over six …

Abstract Introduction and Aim: There is a growing need for better, cheaper and faster
histopathological diagnostic. The authors reviewed the main steps of the efforts towards the …

Cumulative evidence over the last 3 decades suggests that the cardiac interstitium or
extracellular matrix (ECM)‚especially the extracellular collagen matrix (ECCM)‚plays an …

We investigated whether therapeutic drugs given during healing following acute myocardial
infarction (AMI) modify infarct collagens and left ventricular (LV) distensibility. We treated …

Objectives: The objective of the present case series is to describe the histology and surface
ultrastructure of augmented keratinized gingival mucosa in humans during the early healing …