Introduction Irisin is a myokine/adipokine induced by the exercise in mice and humans,
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …

Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

Introduction Patients with axial spondyloarthritis (axSpA) have a high disease burden mainly
due to the rheumatic disease itself, and also exhibit accelerated atherosclerosis, that leads …

Cardiovascular and metabolic diseases are the leading causes of death and disability
worldwide and impose a tremendous socioeconomic burden on individuals as well as the …

Background Cardiovascular disease is the most common cause of mortality and morbidity in
diabetic patients. Insulin resistance has been shown to be reduced by the secretion of irisin …

Irisin, an emerging adipokine, has been involved in the pathogenesis of type 2 diabetes
mellitus (T2DM). However, previous studies evaluating the association between irisin and …

Background FNDC5 is a novel and important player in energy regulation related to glucose
metabolism and insulin levels. Thus, it may affect the incidence of type 2 diabetes mellitus …

Purpose The aim of this study was to provide evidence of the differences in circulating irisin
levels between type 2 diabetes mellitus (T2DM) patients with and without chronic …

Highlights•T2DM is considered a debilitating metabolic disorder characterized by insulin
resistance.•Evidence suggests potential beneficial effects of curcumin on insulin …

Irisin, a novel myokine produced in response to physical activity, promotes white-to-brown
fat transdifferentiation. The name irisin referred to the ancient Greek goddess Iris, the …