Osteoarthritis (OA) is the most common form of arthritis and a degenerative joint cartilage
disease that is the most common cause of disability in the world among the elderly. It leads …

Intrinsically present bioactive cues allow naturally derived materials to mimic important
characteristics of cartilage while also facilitating cellular recruitment, infiltration, and …

Introduction: Evidence on the management of chondral defects of the patella arises from
studies in which the patellofemoral joint was treated together with the femorotibial joint and …

Background: Matrix-induced chondrogenesis (MIC) is a promising treatment option for
critical-size cartilage lesions of the knee; however, there exists substantial heterogeneity in …

Focal chondral defects of the knee are common and their management is challenging. This
study investigated the efficacy and safety of Autologous Matrix-Induced Chondrogenesis …

Background The management of chondral defects of the patellofemoral joint is debated, and
definitive evidence is lacking. This study systematically updated and summarised the current …

Osteochondral lesions represent a major clinical challenge, especially in the elderly.
Traditional treatment strategies, such as arthroplasty or tissue engineering, have limitations …

Background Cartilage defects are debilitating injuries that can reduce quality of life in
patients. However, the poor regenerative properties of cartilage mean that cartilage repair …

Purpose To evaluate autologous matrix-induced chondrogenesis (AMIC) for isolated focal
retropatellar cartilage lesions and the influence of patellofemoral (PF) anatomy on clinical …

Abstract During Autologous Matrix-Induced Chondrogenesis (AMIC), the membrane is often
glued into the chondral defect. However, whether fibrin glue influences cells proliferation …