T-cell subsets in health, infectious disease, and idiopathic CD4+ T lymphocytopenia

J Laurence - Annals of internal medicine, 1993 - acpjournals.org
Purpose: To update our knowledge about normal absolute values for CD4+ and CD8+
peripheral T-lymphocyte subsets and to show how these values are influenced by infectious …

Mycobacterial disease, immunosuppression, and acquired immunodeficiency syndrome

FM Collins - Clinical Microbiology Reviews, 1989 - Am Soc Microbiol
The mycobacteria are an important group of acid-fast pathogens ranging from obligate
intracellular parasites such as Mycobacterium leprae to environmental species such as M …

The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1

JL Fahey, JMG Taylor, R Detels… - … England Journal of …, 1990 - Mass Medical Soc
We evaluated three cellular and five serologic markers that are affected by infection with the
human immunodeficiency virus type 1 (HIV-1) for their ability to predict the progression to …

Acute AIDS retrovirus infection: definition of a clinical illness associated with seroconversion

DA Cooper, P Maclean, R Finlayson, HM Michelmore… - The Lancet, 1985 - Elsevier
In the course of a prospective immunoepidemiological study of homosexual men in Sydney,
seroconversion to the AIDS-associated retrovirus (ARV) was observed in 12 subjects …

pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

BS Stein, SD Gowda, JD Lifson, RC Penhallow… - Cell, 1987 - cell.com
CD4 functions as the cell-surface receptor for human immunodeficiency virus (HIV);
however, the mechanism of virus entry into susceptible cells is unknown. To explore this …

Acquired immunodeficiency syndrome in a heterosexual population in Zaire

P Piot, H Taelman, KB Minlangu, N Mbendi, K Ndangi… - The Lancet, 1984 - Elsevier
Abstract 38 patients with the acquired immunodeficiency syndrome (AIDS) were identified in
Kinshasa, Zaire, during a 3 week period in 1983. The male to female ratio was 1· 1: 1. The …

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

AI Dayton, JG Sodroski, CA Rosen, WC Goh… - Cell, 1986 - cell.com
The trans-activator gene (tat-Ill) of the human T lymphotropic virus type Ill (HTLV-IIIILAV) is
shown to regulate positively the expression of viral proteins. Viruses in which the fat-Ill gene …

Laboratory control values for CD4 and CD8 T lymphocytes. Implications for HIV‐1 diagnosis

M Bofill, G Janossy, CA Lee… - Clinical & …, 1992 - Wiley Online Library
With the advent of standard flow cytometric methods using two‐colour fluorescence on
samples of whole blood, it is possible to establish the ranges of CD3. CD 4 and CDS T …

Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell …

M Clerici, NI Stocks, RA Zajac… - The Journal of …, 1989 - Am Soc Clin Investig
We have tested the T helper cell (TH) potential of asymptomatic, HIV seropositive (HIV+)
patients, using an in vitro assay for IL-2 production. Peripheral blood leukocytes (PBL) from …

Ability of HIV to Promote a TH1 to TH0 Shift and to Replicate Preferentially in TH2 and TH0 Cells

E Maggi, M Mazzetti, A Ravina, F Annunziato… - Science, 1994 - science.org
Both interferon γ (IFN-γ) produced by T helper 1 (TH1) lymphocytes and interleukin-4 (IL-4)
produced by TH2 lymphocytes were reduced in either bulk circulating mononuclear cells or …