Genome-protecting compounds as potential geroprotectors
Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
Mesenchymal stem cells could be considered as a candidate for further studies in cell-based therapy of Alzheimer's disease via targeting the signaling pathways
Mesenchymal stem cells (MSCs) are of particular interest because of their potential in
regenerative medicine. Stem cell-based therapies cast a new hope for neurodegenerative …
regenerative medicine. Stem cell-based therapies cast a new hope for neurodegenerative …
Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter …
The use of mesenchymal stem cells (MSCs) for cell therapy and regenerative medicine has
received widespread attention over the past few years, but their application can be …
received widespread attention over the past few years, but their application can be …
Differential arterial and venous endothelial redox responses to oxidative stress
B Shrestha, PK Prasai, AM Kaskas, A Khanna… - …, 2018 - Wiley Online Library
Objective Oxidative stress is a central event linked with endothelial dysfunction and
inflammation in several vascular pathologies, marked by over‐production of ROS and …
inflammation in several vascular pathologies, marked by over‐production of ROS and …
Low antioxidant glutathione levels lead to longer telomeres: a sex-specific link to longevity?
AA Romero-Haro, J Figuerola… - Integrative Organismal …, 2023 - academic.oup.com
Telomeres are repetitive DNA sequences at the end of chromosomes that protect them from
degradation. They have been the focus of intense research because short telomeres would …
degradation. They have been the focus of intense research because short telomeres would …
Immunocytochemical analysis of valproic acid induced histone H3 and H4 acetylation during differentiation of rat adipose derived stem cells into neuron-like cells
F Rezaei, T Tiraihi, A Abdanipour… - Biotechnic & …, 2018 - Taylor & Francis
Valproic acid (VPA) is an inhibitor of histone deacetylases (HDACs) that can regulate
differentiation and proliferation of stem cells by epigenetic mechanisms. We investigated …
differentiation and proliferation of stem cells by epigenetic mechanisms. We investigated …
[HTML][HTML] Rat adipose-derived mesenchymal stem cells aging reduction by zinc sulfate under extremely low frequency electromagnetic field exposure is associated with …
Zinc as an essential trace element was reported to be involved in regulation of the growth
and aging of cells. In this study, rat adipose-derived mesenchymal stem cells were exposed …
and aging of cells. In this study, rat adipose-derived mesenchymal stem cells were exposed …
Characterization and regulation of carrier proteins of mitochondrial glutathione uptake in human retinal pigment epithelium cells
M Wang, LI Lau, PG Sreekumar, C Spee… - … & Visual Science, 2019 - iovs.arvojournals.org
Purpose: To characterize two mitochondrial membrane transporters 2-oxoglutarate (OGC)
and dicarboxylate (DIC) in human RPE (hRPE) and to elucidate their role in the regulation of …
and dicarboxylate (DIC) in human RPE (hRPE) and to elucidate their role in the regulation of …
[PDF][PDF] Osteogenesis of bone marrow mesenchymal stem cells on nano-hydroxyapatite/bacterial cellulose coposite scaffolds in rats
TQ Song, BJ Ge, HL Chen, XW Yang, F Yuan - Int. J. Clin. Exp. Pathol, 2016 - e-century.us
The composite scaffolds are extensively employed to repair and reconstruct damaged bone
tissue function. The present study was designed to explore the nano-hydroxyapatite …
tissue function. The present study was designed to explore the nano-hydroxyapatite …
A Comparative Study of the Effects of Sodium Selenite and Glutathione Mono Ethyl Ester on Aged Adipose-Derived Stem Cells: The Telomerase and Cellular …
N Aminizadeh, T Tiraihi, SA Mesbah-Namin… - Rejuvenation …, 2018 - liebertpub.com
The proliferation and differentiation potential of adipose-derived stem cells (ADSCs) decline
with aging. Moreover, Alzheimer's disease is associated with progressive decline in …
with aging. Moreover, Alzheimer's disease is associated with progressive decline in …