DL Seger, JK Loden - Clinical Toxicology, 2018 - Taylor & Francis
Context: Following clonidine ingestion, naloxone is seldom administered as it is considered ineffective in reversing somnolence, bradycardia, or hypotension. However, this conclusion …
LK Choon, AI Khiruddin, WMWM Annuar… - Turkish Journal of …, 2023 - journals.lww.com
Xylazine is a type of sedative commonly used in veterinary medicine. It acts on the central alpha-2 receptor and suppresses norepinephrine release from the peripheral nerve …
NB Menke, SJ Walsh, AM King - Emergency Medicine Clinics, 2015 - emed.theclinics.com
Cardiac contractility requires the rhythmic generation of a myocardial action potential conducted through the heart to coordinate myocardial contractions. Molecular studies have …
When considering toxic chemicals in the environment, a mechanistic, causal explanation of toxicity may be preferred over a statistical or machine learning-based prediction by itself …
X Li, X Hu, F Yang, L Yuan, J Cai, G Hu - Chemico-Biological Interactions, 2019 - Elsevier
Background and objectives Clonidine has been clinically used to treat Tourette's syndrome for decades. There was research finding that clonidine possessed the best risk-benefit ratio …
L Guo, Y Yu, N Xin, J Sun, Y Chen, M Yu - Journal of Molecular …, 2018 - Springer
Exposure of neonatal animals to anesthetics may cause developmental functional changes and acute structural anomalies in the brain. Clonidine, an α2-adrenoceptor agonist …
AL Cates, SM Wheatley, KD Katz - Pediatric Emergency Care, 2018 - journals.lww.com
A 22-month-old girl without any significant medical history accidentally consumed a small amount of a therapeutic compounding cream that contained camphor, gabapentin …
SA Al-Abri, HS Yang, KR Olson - Journal of Medical Toxicology, 2014 - Springer
An 18-month-old child was brought to the emergency department (ED) by his mother for evaluation of diarrhea, vomiting, and somnolence. He was lethargic, with “pinpoint” pupils …
Background Tizanidine, an α-2 adrenoceptor agonist, is widely prescribed for the management of spasticity in adults. Case reports on pediatric tizanidine overdose are …