A recent hypothesis to enter the literature suggests that glaucoma is a neurodegenerative
disease. The basis for this has been the finding of central nervous system changes in …

Background: Glaucoma is a leading cause of irreversible blindness worldwide. The
increasing interest in the involvement of the cortical visual pathway in glaucomatous patients …

Background Longitudinal evidence of poor visual acuity associating with higher risk of
incident dementia is mixed. This study aimed to examine if poor visual acuity was associated …

Our aim was to assess in primary open angle glaucoma (POAG), a major cause of
irreversible blindness worldwide, whether diffuse brain changes recently shown in …

Glaucoma is the second leading cause of blindness worldwide and its pathogenesis
remains unclear. In this study, we measured the structure, metabolism and function of the …

Glaucoma, one of the leading causes of blindness worldwide, affects primarily retinal
ganglion cells (RGCs) and their axons. The pathophysiology of glaucoma is not fully …

Brain changes within and beyond the visual system have been demonstrated in primary
open angle glaucoma (POAG), the most common type of glaucoma. These changes have …

In rats and mice, limbar tissues of the left eye were laser-photocoagulated (LP) and ocular
hypertension (OHT) effects were investigated 1 week to 6 months later. To investigate the …

Primary open-angle glaucoma (POAG) has been suggested to be a neurodegenerative
disease associated with altered cerebral vascular hemodynamics and widespread …

To study short and long-term effects of acute ocular hypertension (AOHT) on inner and outer
retinal layers, in adult Sprague-Dawley rats AOHT (87 mmHg) was induced for 90 min and …