Polyphenols in metabolic diseases

A Gasmi, PK Mujawdiya, S Noor, R Lysiuk… - Molecules, 2022 - mdpi.com
Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or
more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic …

Caffeic acid on metabolic syndrome: A review

NN Muhammad Abdul Kadar, F Ahmad, SL Teoh… - Molecules, 2021 - mdpi.com
Metabolic syndrome (MetS) is a constellation of risk factors that may lead to a more sinister
disease. Raised blood pressure, dyslipidemia in the form of elevated triglycerides and …

Beneficial effects of citrus flavanones naringin and naringenin and their food sources on lipid metabolism: An update on bioavailability, pharmacokinetics, and …

Y Yang, M Trevethan, S Wang, L Zhao - The Journal of nutritional …, 2022 - Elsevier
Naringin and naringin's aglycone naringenin belong to a subclass of flavonoids called
flavanones. While many studies of pure naringenin and naringin and their food sources …

Therapeutic effects and safe uses of plant-derived polyphenolic compounds in cardiovascular diseases: a review

BS Alotaibi, M Ijaz, M Buabeid, ZJ Kharaba… - Drug design …, 2021 - Taylor & Francis
Polyphenols have long been recognized as health-promoting entities, including beneficial
effects on cardiovascular disease, but their reputation has been boosted recently following a …

[HTML][HTML] Nephroprotective effect of naringin in methotrexate induced renal toxicity in male rats

H Elsawy, AM Alzahrani, M Alfwuaires… - Biomedicine & …, 2021 - Elsevier
Highlights•Naringin induced a marked decrease of renal injury markers in MTX-treated
rats.•Naringin protected against redox imbalance of renal tissue in MTX-treated …

Control of reactive oxygen species for the prevention of Parkinson's disease: the possible application of flavonoids

TY Kim, E Leem, JM Lee, SR Kim - Antioxidants, 2020 - mdpi.com
Oxidative stress reflects an imbalance between the production of reactive oxygen species
(ROS) and antioxidant defense systems, and it can be associated with the pathogenesis and …

Naringin ameliorates type 2 diabetes mellitus-induced steatohepatitis by inhibiting RAGE/NF-κB mediated mitochondrial apoptosis

AA Syed, MI Reza, M Shafiq, S Kumariya, P Singh… - Life sciences, 2020 - Elsevier
Aims Recent findings have instituted the role of hyperglycemia-related AGE/RAGE and NF-
κB in instigating reactive oxygen species (ROS) mediated mitochondrial dysfunction and …

Naringin: nanotechnological strategies for potential pharmaceutical applications

S Ravetti, AG Garro, A Gaitán, M Murature, M Galiano… - Pharmaceutics, 2023 - mdpi.com
Polyphenols comprise a number of natural substances, such as flavonoids, that show
interesting biological effects. Among these substances is naringin, a naturally occurring …

Protective effects of naringin against drugs and chemical toxins induced hepatotoxicity: a review

K Shirani, BS Yousefsani, M Shirani… - Phytotherapy …, 2020 - Wiley Online Library
The liver is a vital metabolic organ for drug and xenobiotic metabolism which is influenced
by chemical and natural toxins. Liver injury is associated with systemic oxidative stress …

Citrus Flavonoids: Biological Activities, Implementation in Skin Health, and Topical Applications: A Review

Z Sebghatollahi, M Ghanadian, P Agarwal… - ACS Food Science & …, 2022 - ACS Publications
Citrus fruits are one of the most popular sources of dietary flavonoids, such as hesperidin,
hesperetin, naringin, naringenin, quercetin, rutin, diosmin, diosmetin, kaempferol, myricetin …