Granulocytes are innate immune effector cells with essential functions in host resistance to
bacterial infections. I will discuss emerging evidence that during Mycobacterium tuberculosis …

Tuberculosis (TB) remains a significant global health challenge, claiming the lives of up to
1.5 million individuals annually. TB is caused by the human pathogen Mycobacterium …

Rationale Severe viral respiratory infections are often characterised by extensive myeloid
cell infiltration and activation and persistent lung tissue injury. However, the immunological …

This fifth edition volume expands on the previous editions by presenting readers with the
latest developments and emerging methodologies in cytometry. The chapters in this book …

Lung inflammation indicated by 18F-labeled fluorodeoxyglucose (FDG) in patients with
tuberculosis is associated with disease severity and relapse risk upon treatment completion …

Autosomal dominant loss-of-function (LoF) variants in cytotoxic T-lymphocyte associated
protein 4 (CTLA4) cause immune dysregulation with autoimmunity, immunodeficiency and …

Background Tuberculosis (TB) is an infectious disease caused by Mycobacterium
tuberculosis (Mtb) infection. Cuproptosis is a novel cell death mechanism correlated with …

Oxysterols (ie, oxidized cholesterol species) have complex roles in biology. 25-
Hydroxycholesterol (25HC), a product of the activity of cholesterol-25-hydroxylase (CH25H) …

Pathogenic mycobacteria orchestrate the complex cell populations known as granuloma that
is the hallmark of tuberculosis. Foam cells, a lipid-rich cell-type, are considered critical for …

Eosinophils are important mediators of mucosal tissue homeostasis, anti-helminth
responses, and allergy. Lung eosinophilia has previously been linked to aberrant Type 2 …