Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Abstract Compound 3c (5-(4-(dimethylamino) phenyl)-3-(thiophen-2-yl)-pyrazoline-1-
carbothioamide) was synthesized and characterized experimentally using UV-Vis, FT-IR …

Abstract A novel series pyrrolo [3, 2-b] pyridine-3-carboxamide linked 2-methoxypyridine
derivatives have been designed, synthesized and confirmed by FT-IR, 1H NMR, 13C NMR …

Heterocyclic hybrid frameworks represent a burgeoning domain within the realms of drug
discovery and medicinal chemistry, attracting considerable attention in recent years …

This study deals with the design and synthesis of new pyrazoline-thiazole scaffold as
promising anti-cancer agents, with the goal of building new compounds with combinations of …

Several pyrazole‐thiazole hybrids featuring two potentially bioactive pharmacophores with
or without linker have been synthesized using the molecular hybridization approach as …

Background: Pyrazoline is a heterocyclic compound with five members, two nitrogen atoms
in a circle, and one endocyclic bond. Pyrazoline is a popular electron-rich nitrogen carrier …

Pyrazoline are structurally versatile nitrogen-containing heterocycle that has gained more
attention owing to its diversified pharmacological activities. This special scaffold serves as a …

The binding mechanism of a new and possible drug candidate pyrazoline derivative
compound K4 and bovine serum albumin (BSA) was investigated in buffer solution (pH 7.4) …