[HTML][HTML] Multitarget Pharmacology of Sulfur–Nitrogen Heterocycles: Anticancer and Antioxidant Perspectives

A Drakontaeidi, I Papanotas, E Pontiki - Antioxidants, 2024 - mdpi.com
Cancer and oxidative stress are interrelated, with reactive oxygen species (ROS) playing
crucial roles in physiological processes and oncogenesis. Excessive ROS levels can induce …

A mini-review on pharmacological importance of benzothiazole scaffold

M Asif, M Imran - Mini-Reviews in Organic Chemistry, 2021 - ingentaconnect.com
Heterocyclic compounds are important because they have almost all types of
pharmacological properties. Due to these properties of heterocyclic compounds, they …

Green synthesis and biological evaluation of 6-substituted-2-(2-hydroxy/methoxy phenyl) benzothiazole derivatives as potential antioxidant, antibacterial and …

L Racané, L Ptiček, G Fajdetić, V Tralić-Kulenović… - Bioorganic …, 2020 - Elsevier
We present a new efficient green synthetic protocol for introduction of substituents to the C-6
position of 2-arylbenzothiazole nuclei. Newly synthesized compounds were designed to …

Biological activity and computational analysis of novel acrylonitrile derived benzazoles as potent antiproliferative agents for pancreatic adenocarcinoma with …

A Beč, L Persoons, D Daelemans, K Starčević… - Bioorganic …, 2024 - Elsevier
Continuing our research into the anticancer properties of acrylonitriles, we present a study
involving the design, synthesis, computational analysis, and biological assessment of novel …

[PDF][PDF] A review on recent development and biological applications of benzothiazole derivatives

HS Lihumis, AA Alameri, RH Zaooli - Prog. Chem. Biochem. Res, 2022 - sid.ir
Benzothiazoles are heterocyclic dicyclic compounds consisting of a benzene bonded to
amembered ring containing nitrogen and sulfur atoms [1] It possesses a number of …

Synthetic approaches to biologically active C-2-substituted benzothiazoles

BA Shainyan, LV Zhilitskaya, NO Yarosh - Molecules, 2022 - mdpi.com
Numerous benzothiazole derivatives are used in organic synthesis, in various industrial and
consumer products, and in drugs, with a wide spectrum of biological activity. As the …

Electrochemical oxidation and superoxide radical scavenging activity of 2-hydroxy/methoxy-phenylbenzothiazole derivatives

IN Jovanović, R Vianello, D Jadreško, L Racané… - Journal of …, 2023 - Elsevier
Electrochemical characterisation and antioxidant activity against superoxide radical anion of
four 2-hydroxy/methoxy-phenylbenzothiazole derivatives (1–4) are reported. The …

Experimental and computational study of the antioxidative potential of novel nitro and amino substituted benzimidazole/benzothiazole-2-carboxamides with …

M Cindrić, I Sović, M Mioč, L Hok, I Boček, P Roškarić… - Antioxidants, 2019 - mdpi.com
We present the synthesis of a range of benzimidazole/benzothiazole-2-carboxamides with a
variable number of methoxy and hydroxy groups, substituted with nitro, amino, or amino …

Chemistry of biologically active benzimidazole scaffolds: medicinal chemistry perspective

A Bendi, Sangeeta, L Singh… - Mini-Reviews in Organic …, 2022 - benthamdirect.com
Nowadays, heterocyclic compounds have attained a prominent place among the various
classes of aromatic organic compounds. Benzimidazoles are important classes of …

Contemporary progress in the synthesis and reaction of 2-arylbenzothiazole: a review

A Sethiya, N Sahiba, J Soni, D Gandhi… - Current Organic …, 2018 - ingentaconnect.com
Benzothiazole (BOT), the heterocyclic system consists of five-membered thiazole ring fused
with the benzene ring. It is a very potent molecule because of its numerous pharmacological …