A total of 378 novel drugs and 27 biosimilars approved by the US Food and Drug
Administration (FDA) between 2010 and 2019 were evaluated according to approval …

The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

This article provides an update on the global cancer burden using the GLOBOCAN 2020
estimates of cancer incidence and mortality produced by the International Agency for …

Primary liver cancer, the major histology of which is hepatocellular carcinoma (HCC), is the
second leading cause of cancer death worldwide. We comprehensively examined recent …

METHODS We conducted a systematic study which represents one of the most
comprehensive effort to quantify global HCV epidemiology, using the best available …

Background: Rapid improvements in hepatitis C virus (HCV) therapy have led to the
approval of multiple oral direct-acting antiviral (DAA) regimens by the US Food and Drug …

Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

Hepatitis C virus (HCV) exhibits high genetic diversity, characterized by regional variations
in genotype prevalence. This poses a challenge to the improved development of vaccines …

Primary liver cancer is the sixth most commonly occurring cancer in the world and the
second largest contributor to cancer mortality. 1 Globally, the most common histology …