BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

Sperm are transcriptionally and translationally quiescent and, therefore, rely on the seminal
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …

Extracellular vesicles (EVs) have considerable potential as diagnostic, prognostic, and
therapeutic agents, in large part because molecular patterns on the EV surface betray the …

Glycosylation is one of the most important post-translational modifications of proteins and
plays an essential role in spermatogenesis, maturation, extracellular quality control …

Background The exosome is a critical component of the intercellular communication.,
playing a vital role in regulating cell function. These small vesicles contain proteins, mRNAs …

Purification of extracellular vesicles for research and therapeutic applications requires
updated methodology to address the limitations of traditional ultracentrifugation and other …

Glycosylation plays a pivotal role in the physiological and pathological processes of male
reproduction. It impacts thousands of proteins and is actively ongoing through all stages of …

In light of recent research, there is increasing evidence showing that extracellular semen
components have a significant impact on the immune reaction of the female partner, leading …

Environmental pollution, chronic stress, and unhealthy lifestyle are factors that negatively
affect reproductive potential. Currently, 15–20% of couples in industrialized countries face …

Background: Human seminal prostasomes are intrinsically heterogeneous extracellular
vesicles (EVs) whose composition is, additionally, influenced by different physiological …