Toxoplasmosis is a parasitic disease affecting human, livestock and cat. Prophylactic
strategies would be ideal to prevent infection. In a One Health vaccination approach, the …

Toxoplasma gondii is an obligate intracellular protozoan with the ability to infect virtually any
type of nucleated cell in warm‐blooded vertebrates including humans. Toxoplasma gondii …

Upon pathogen detection, macrophages normally stay sessile in tissues while dendritic cells
(DCs) migrate to secondary lymphoid tissues. The obligate intracellular protozoan …

The recrudescence of Toxoplasma cysts is the cause of clinical disease in the
immunocompromised. Although Toxoplasma has been a useful parasite model for decades …

The murine innate immune response against Toxoplasma gondii is predominated by the
interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans …

Pseudomonas aeruginosa is an opportunistic pathogen that causes life-threatening
infections in cystic fibrosis patients and immunocompromised individuals. A tightly regulated …

Dendritic cells and macrophages are integral parts of the innate immune system and
gatekeepers against infection. The protozoan pathogen, Toxoplasma gondii, is known to …

The factors that determine the outcomes of host–pathogen interactions, such as host
specificity, tissue specificity, and transition from asymptomatic to symptomatic behavior of a …

Emerging evidence indicates the early growth response 1 (Egr1) plays an important role in
the pathogenesis of chronic pain. However, the regulation of Egr1 expression in the DRG …

Cardiac glycosides (CGs) constitute a group of steroid-like compounds renowned for their
effectiveness in treating cardiovascular ailments. In recent times, there has been growing …