Electrochemistry represents one of the most intimate ways of interacting with molecules. This
review discusses advances in synthetic organic electrochemistry since 2000. Enabling …

Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …

Meeting the demand for sugars: The importance of oligosaccharides and glycoconjugates in
biological systems has stimulated a need to access significant amounts of these …

Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve druglike physical and …

Abstract Die wichtige Rolle, die Oligosaccharide und Glycokonjugate in biologischen
Systemen spielen, erfordert immer neue und vor allem größere Mengen dieser Moleküle …

Carbohydrates carrying an aromatic aglycon are important natural products and thus key
synthetic targets. However, due to the electron-withdrawing properties of aromatic rings …

We described a novel palladium-catalyzed domino procedure for the preparation of (hetero)
aryl thio/selenoglycosides. Readily available (hetero) aryl iodides and easily accessible 1 …

An efficient α-selective glycosylation method was developed for the synthesis of 2-deoxy-2-
amino-d-glucosides based on synergetic α-directing effects of the TolSCl/AgOTf promotion …

Halogen bonding is the formation of a non‐covalent interaction between an electrophilic
halogen substituent and a Lewis base, for instance, a halide. These kinds of relatively weak …

Traditional strategies for oligosaccharide synthesis often require extensive protecting and/or
leaving group manipulations between each glycosylation step, thereby increasing the total …