The continuous emergence and rapid spread of a multidrug-resistant strain of bacterial
pathogens have demanded the discovery and development of new antibacterial agents. A …

Similar to its eukaryotic counterpart, the prokaryotic cytoskeleton is essential for the
structural and mechanical properties of bacterial cells. The essential protein FtsZ is a central …

Antimicrobial resistance to virtually all clinically applied antibiotic classes severely limits the
available options to treat bacterial infections. Hence, there is an urgent need to develop and …

A new and suitable multicomponent one-pot reaction was developed for the synthesis of 2-
amino-3-cyanopyridine derivatives. Background: This synthesis was demonstrated by the …

Natural products (NPs) are inexhaustible wellsprings for new agrochemicals discovery. To
excavate novel natural products-based antibacterial leads or candidates potentially …

Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public
health. Thus, identification of new targets and development of new antibacterial agents are …

Tuberculosis (TB) is a severe infectious disease worldwide. The increasing emergence of
drug‐resistant Mycobacterium tuberculosis (Mtb) has markedly hampered TB control …

With the emergence of multidrug-resistant bacterial strains, there is a dire need for new drug
targets for antibacterial drug discovery and development. Filamentous temperature sensitive …

In recent years, the rise of antibiotic resistance has become a primary health problem. With
the emergence of bacterial resistance, the need to explore and develop novel antibacterial …

Crocin, a component of saffron spice, is known to have an anticancer activity. However, the
targets of crocin are not known. In this study, crocin was found to inhibit the proliferation of …