Oxidative stress in traumatic brain injury

A Fesharaki-Zadeh - International journal of molecular sciences, 2022 - mdpi.com
Traumatic Brain Injury (TBI) remains a major cause of disability worldwide. It involves a
complex neurometabolic cascade, including oxidative stress. The products of this …

Recent advances in pathophysiology of traumatic brain injury

P Kaur, S Sharma - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Traumatic brain injury (TBI) constitutes the primary reason for mortality and
morbidity in persons worldwide below 45 years of age. 1.7 million Traumatic events occur …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Traumatic brain injury: oxidative stress and novel anti-oxidants such as mitoquinone and edaravone

H Ismail, Z Shakkour, M Tabet, S Abdelhady, A Kobaisi… - Antioxidants, 2020 - mdpi.com
Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on
severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic …

Pathophysiology of traumatic brain injury

C Werner, K Engelhard - British journal of anaesthesia, 2007 - academic.oup.com
The knowledge of the pathophysiology after traumatic head injury is necessary for adequate
and patient-oriented treatment. As the primary insult, which represents the direct mechanical …

Repeated mild traumatic brain injury: potential mechanisms of damage

B Fehily, M Fitzgerald - Cell transplantation, 2017 - journals.sagepub.com
Mild traumatic brain injury (mTBI) represents a significant public healthcare concern,
accounting for the majority of all head injuries. While symptoms are generally transient …

N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology

JR Moffett, B Ross, P Arun, CN Madhavarao… - Progress in …, 2007 - Elsevier
The brain is unique among organs in many respects, including its mechanisms of lipid
synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …

Mitochondria in traumatic brain injury and mitochondrial‐targeted multipotential therapeutic strategies

G Cheng, R Kong, L Zhang… - British journal of …, 2012 - Wiley Online Library
Traumatic brain injury (TBI) is a major health and socioeconomic problem throughout the
world. It is a complicated pathological process that consists of primary insults and a …

Assessment of metabolic brain damage and recovery following mild traumatic brain injury: a multicentre, proton magnetic resonance spectroscopic study in concussed …

R Vagnozzi, S Signoretti, L Cristofori, F Alessandrini… - Brain, 2010 - academic.oup.com
Concussive head injury opens a temporary window of brain vulnerability due to the
impairment of cellular energetic metabolism. As experimentally demonstrated, a second mild …

A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after …

M Du, C Wu, R Yu, Y Cheng, Z Tang, B Wu, J Fu… - Molecular …, 2022 - nature.com
Traumatic brain injury (TBI) can lead to different neurological and psychiatric disorders.
Circular RNAs (circRNAs) are highly expressed in the nervous system and enriched in …