Background. Exchange transfusion (ET) has biologic plausibility as an adjunct to
antimalarial drugs in treating severe malaria and has been used for decades despite limited …

In France, sickle cell disease (SCD) is the most common rare disease and represents the
most prevalent genetic disorder, with 19,800 to 32,400 patients diagnosed in 2016 and 1 …

Fat embolism syndrome is a devastating complication of sickle cell disease resulting from
extensive bone marrow necrosis and associated with high mortality rates, while survivors …

Current definitions of acute chest syndrome (ACS) in sickle cell anemia (SCA) do not
account for rapid progression of respiratory compromise. In this two‐center retrospective …

Objective: With increasing survival rates in childhood acute lymphocytic leukemia (ALL), the
long-term side effects of treatment have become important. Our aim was to investigate health …

Objective: Sickle cell disease is associated with a decreased life expectancy, half of the
deaths occurring in the ICU. We aimed to describe the characteristics of sickle cell disease …

Sickle cell disease (SCD) is characterized by increased cellular adhesiveness, hemolytic
anemia, hemostatic activation, vaso-occlusion and thrombosis. We found that patients with …

BACKGROUND Depletion of haptoglobin (Hp) and hemopexin (Hx) with increase in free
hemoglobin and heme are important etiologies of vaso‐occlusive complications in sickle cell …

Thrombotic microangiopathy (TMA) in patients with sickle cell disease (SCD) is a rare
complication. These patients manifest microangiopathic hemolytic anemia (MAHA) with …

Plasmapheresis may improve clinical condition in sickle cell disease through its effects on red
blood cell rheology Plasmapheresis may improve clinical condition in sickle cell disease …