[HTML][HTML] Intestinal colonization resistance in the context of environmental, host, and microbial determinants

S Woelfel, MS Silva, B Stecher - Cell Host & Microbe, 2024 - cell.com
Microbial communities that colonize the human gastrointestinal (GI) tract defend against
pathogens through a mechanism known as colonization resistance (CR). Advances in …

A long journey to treat epilepsy with the gut microbiota

Q Li, Y Gu, J Liang, Z Yang, J Qin - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Epilepsy is a common neurological disorder that affects approximately 10.5 million children
worldwide. Approximately 33% of affected patients exhibit resistance to all available …

[HTML][HTML] Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis

H Chen, X Fu, X Wu, J Zhao, F Qiu, Z Wang, Z Wang… - Bone Research, 2024 - nature.com
Rheumatoid arthritis (RA) is an autoimmune disease. Early studies hold an opinion that gut
microbiota is environmentally acquired and associated with RA susceptibility. However …

Intestinal persistence of Bifidobacterium infantis is determined by interaction of host genetics and antibiotic exposure

Y Wang, JM Choo, AC Richard… - The ISME …, 2024 - academic.oup.com
Probiotics have gained significant attention as a potential strategy to improve health by
modulating host–microbe interactions, particularly in situations where the normal microbiota …

Disentangle beneficial effects of strain engraftment after fecal microbiota transplantation in subjects with MetSyn

EWJ van der Vossen, M Davids, B Voermans… - Gut …, 2024 - Taylor & Francis
ABSTRACT Fecal Microbiota Transplantation (FMT) has emerged as a potential modality for
mitigating microbiome-associated diseases. Despite this potential, the precise causal …

Future in the past: paternal reprogramming of offspring phenotype and the epigenetic mechanisms

D Wu, K Zhang, K Guan, FA Khan… - Archives of …, 2024 - Springer
That certain preconceptual paternal exposures reprogram the developmental phenotypic
plasticity in future generation (s) has conceptualized the “paternal programming of offspring …

[HTML][HTML] Dose-Responsive Effects of Iron Supplementation on the Gut Microbiota in Middle-Aged Women

J Shearer, S Shah, MJ MacInnis, G Shen-Tu, C Mu - Nutrients, 2024 - mdpi.com
Oral iron supplementation is the first-line treatment for addressing iron deficiency, a concern
particularly relevant to women who are susceptible to sub-optimal iron levels. Nevertheless …

[HTML][HTML] Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach

Q Zhang, D Schwarz, Y Cheng, Y Sohrabi - Trends in Molecular Medicine, 2024 - cell.com
The ability of the gut microbiome to adapt to a new environment and utilize a new metabolite
or dietary compound by inducing structural variations (SVs) in the genome has an important …

New dawn of ginsenosides: regulating gut microbiota to treat metabolic syndrome

X Bai, R Fu, J Deng, H Yang, C Zhu, D Fan - Phytochemistry Reviews, 2024 - Springer
Metabolic Syndrome (MS) is an amalgamation of symptoms encompassing insulin
resistance, obesity, dyslipidemia, elevated fasting blood glucose levels, and hepatic …

[HTML][HTML] Bowel function and inflammation: Is motility the other side of the coin?

A Panarese - World Journal of Gastroenterology, 2024 - ncbi.nlm.nih.gov
Digestion and intestinal absorption allow the body to sustain itself and are the emblematic
functions of the bowel. On the flip side, functions also arise from its role as an interface with …