Prolactin is a protein hormone of the anterior pituitary gland that was originally named for its
ability to promote lactation in response to the suckling stimulus of hungry young mammals …

Prolactin (PRL) has a dual function–as a circulating hormone and as a cytokine. This
understanding is based on PRL production and distinct regulation in extrapituitary sites, its …

Gene induction and categorical reprogramming during in vitro human endometrial fibroblast
decidualization. Physiol Genomics 7: 135–148, 2001. First published September 21, 2001; …

Background Decidualization, the differentiation process of maternal uterine stromal cells into
secretory decidual cells, is a prerequisite for successful implantation and progression of …

The oxidation and isomerization of 3beta-hydroxy-5-ene steroids into keto-4-ene steroids, a
pivotal step in the synthesis of all hormonal steroids, is catalyzed by several isoforms of …

Transcriptional regulation of the prolactin gene in the decidua differs from that in the
pituitary. Several lines of evidence strongly suggest this difference is due to regulation of the …

Deletion analysis of the human PRL promoter in endometrial stromal cells decidualized in
vitro revealed a 536-bp enhancer located between nucleotide (nt)− 2,040 to− 1,505 in the …

In addition to the pituitary, prolactin (PRL) in humans is produced at non-pituitary sites where
it acts as a cytokine. We previously reported that PRL is expressed and released from breast …

Objective: To determine paracrine effects of monocytes/macrophages on c-Jun
dephosphorylation and AP-1 DNA binding activity in human endometrial stromal cells. Study …

During the late luteal phase of the menstrual cycle, human endometrial stromal cells, under
the influence of progesterone and estradiol, differentiate to decidual cells by a process …