The study of protein subcellular distribution, their assembly into complexes and the set of
proteins with which they interact with is essential to our understanding of fundamental …

The stability of proteins influences their tendency to aggregate, undergo degradation, or
become modified in cells. Despite their significance to understanding protein folding and …

Here we discuss, how by applying chemical concepts to biological problems, methods have
been developed to map spatiotemporal regulation of proteins and small-molecule …

Although there is much focus on the impact of mutations on structured protein domains, less
is known about their impact on unstructured regions. In this issue, Meyer et al. demonstrate …

Using computational techniques to identify intrinsically disordered residues is practical and
effective in biological studies. Therefore, designing novel high-accuracy strategies is always …

Folding stabilities determine the propensity of proteins to aggregate, degrade, or become
modified in cells. However, despite their significance for understanding protein folding and …