The Baldwin rules constitute one of the clearest examples of the success which can be
obtained through the application of stereoelectronic concepts to reaction design. With …

Conspectus Do not bend the triple bonds! This familiar undergraduate mantra must be
disobeyed if the alkyne group is used as a building block in molecular construction. This …

Controlling selectivity of reactions is an ongoing quest in chemistry. In this work, we
demonstrate reversible and selective bond formation and dissociation promoted by tip …

This review outlines fundamental factors responsible for hybridization trends in organic and
main group compounds. Hybridization is a classic chemical concept that transcends …

Spatial orthogonality of the two independently addressable π-systems in alkynes can be
used for the design and control of metal-free cascade transformations. Examples include …

This work introduces an approach to uncoupling electrons via maximum utilization of
localized aromatic units, ie, the Clar's π-sextets. To illustrate the utility of this concept to the …

The synergy between bond formation and bond breaking that is typical for pericyclic
reactions is lost in their mechanistic cousins, cycloaromatization reactions. In these …

Kinetics of the reactions of aryldiazomethanes (ArCHN2) with benzhydrylium ions (Ar2CH+)
have been measured photometrically in dichloromethane. The resulting second-order rate …

Chemoselective interaction of aromatic enynes with Bu3Sn radicals can be harnessed for
selective cascade transformations, yielding either Sn-substituted naphthalenes or Sn …

A broad computational analysis of carbon-centered radical formation via the loss of either
CO2 or SO2 from the respective RXO2 radical precursors (X= C or S) reveals dramatic …