Conserved and divergent mechanisms of inner kinetochore assembly onto centromeric chromatin
Kinetochores are large protein complexes built on centromeric chromatin that mediate
chromosome segregation. The inner kinetochore, or constitutive centromere-associated …
chromosome segregation. The inner kinetochore, or constitutive centromere-associated …
[HTML][HTML] Canonical and noncanonical regulators of centromere assembly and maintenance
C Salinas-Luypaert, D Fachinetti - Current Opinion in Cell Biology, 2024 - Elsevier
Centromeres are specialized chromosomal domains where the kinetochores assemble
during cell division to ensure accurate transmission of the genetic information to the two …
during cell division to ensure accurate transmission of the genetic information to the two …
Centromere/kinetochore is assembled through CENP-C oligomerization
Kinetochore is an essential protein complex required for accurate chromosome segregation.
The constitutive centromere-associated network (CCAN), a subcomplex of the kinetochore …
The constitutive centromere-associated network (CCAN), a subcomplex of the kinetochore …
Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells
JH Cao, T Hori, M Ariyoshi… - Journal of cell …, 2024 - journals.biologists.com
The kinetochore is an essential structure for chromosome segregation. Although the
kinetochore is usually formed on a centromere locus, it can be artificially formed at a non …
kinetochore is usually formed on a centromere locus, it can be artificially formed at a non …
Direct recruitment of Mis18 to interphase spindle pole bodies promotes CENP-A chromatin assembly
N London, B Medina-Pritchard, C Spanos, J Rappsilber… - Current Biology, 2023 - cell.com
CENP-A chromatin specifies mammalian centromere identity, and its chaperone HJURP
replenishes CENP-A when recruited by the Mis18 complex (Mis18C) via M18BP1/KNL2 to …
replenishes CENP-A when recruited by the Mis18 complex (Mis18C) via M18BP1/KNL2 to …
Centromeric localization of αKNL2 and CENP-C proteins in plants depends on their centromere-targeting domain and DNA-binding regions
SP Yalagapati, U Ahmadli, A Sinha… - Nucleic Acids …, 2024 - academic.oup.com
In eukaryotes, accurate chromosome segregation during cell division relies on the
centromeric histone H3 variant, CENH3. Our previous work identified KINETOCHORE …
centromeric histone H3 variant, CENH3. Our previous work identified KINETOCHORE …
Exploration of the biological mechanisms of CENPA as an oncogene in glioma: Screening based on cancer functional status
Y Ling, W Teng, N Long, W Qiu, R Wei… - Journal of Cellular …, 2024 - Wiley Online Library
Glioma is the most common primary tumour in central nervous system, characterized by high
invasiveness, a high recurrence rate and extremely poor prognosis. Machine learning based …
invasiveness, a high recurrence rate and extremely poor prognosis. Machine learning based …
Centromeric localization of KNL2 and CENP-C proteins in plants depends on their centromere-targeting domain and DNA-binding regions
SP Yalagapati, U Ahmadli, A Sinha, M Kalidass… - bioRxiv, 2024 - biorxiv.org
In eukaryotic organisms, proper chromosome segregation during cell division depends on
the centromeric histone H3 (CENH3) variant. Our previous studies identified a plant CENH3 …
the centromeric histone H3 (CENH3) variant. Our previous studies identified a plant CENH3 …
Direct recruitment of Mis18 to interphase spindle poles promotes CENP-A chromatin assembly
N London, B Medina-Pritchard, C Spanos, J Rappsilber… - bioRxiv, 2023 - biorxiv.org
CENP-A chromatin specifies mammalian centromere identity, and its chaperone HJURP
replenishes CENP-A when recruited by the Mis18 complex (Mis18C) via M18BP/KNL2 to …
replenishes CENP-A when recruited by the Mis18 complex (Mis18C) via M18BP/KNL2 to …
An updated view of the kinetochore architecture
M Ariyoshi, T Fukagawa - Trends in Genetics, 2023 - cell.com
The kinetochore is a supramolecular complex that facilitates faithful chromosome
segregation by bridging the centromere and spindle microtubules. Recent functional and …
segregation by bridging the centromere and spindle microtubules. Recent functional and …